Volume 83, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Immunity to saliva of protects against infection as determined by co-inoculation of parasites with salivary gland homogenates (SGHs) of this vector. These results were obtained with long-term colonized female . We investigated the effect of pre-immunization with SGH of long-term colonized against infection co-inoculated with SGH of wild-caught . Our results showed that pre-exposure to SGH of long-term, colonized do not confer protection against infection with co-inoculated with SGH of wild-caught . These preliminary results strongly suggest that the effectiveness of a vector saliva-based vaccine derived from colonized sand fly populations may be affected by inconsistent immune response after natural exposure.


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  • Received : 17 Nov 2009
  • Accepted : 23 Apr 2010
  • Published online : 07 Sep 2010

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