Volume 82, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The first confirmed case of infection in the New World (Buenos Aires, Argentina) is described. To date, only two cases of human infection had been reported in Europe. The patient, a woman, had a fever, a palpable purpuric rash on the upper and lower extremities, and a skin lesion (eschar) on the right leg compatible with tache noire. When interviewed, she reported having had contact with dog ticks. After treatment with doxycycline for 12 days, her symptoms resolved. infection was diagnosed by molecular-based detection of the microorganism in a biopsy specimen of the eschar.


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  1. Beati L, Raoult D, , 1993. Rickettsia massiliae sp. nov., a new spotted fever group Rickettsia . Int J Syst Bacteriol 43: 839840.[Crossref]
  2. Tissot Dupont H, Cornet JP, Raoult D, , 1994. Identification of rickettsiae from ticks collected in the Central African Republic using the polymerase chain reaction. Am J Trop Med Hyg 50: 373380.
  3. Oteo JA, Portillo A, Santibáñez S, Pérez-Martínez L, Blanco JR, Jiménez S, Ibarra V, Pérez-Palacios A, Sanz M, , 2006. Prevalence of spotted fever group Rickettsia species detected in ticks in La Rioja, Spain. Ann NY Acad Sci 1078: 320323.[Crossref]
  4. Eremeeva M, Bosserman EA, Demma LJ, Zambrano LM, Blau DM, Dasch G, , 2006. Isolation and identification of Rickettsia massiliae from Rhipicephalus sanguineus ticks collected in Arizona. Appl Environ Microbiol 72: 55695577.[Crossref]
  5. Cardeñosa N, Segura F, Raoult D, , 2003. Serosurvey among Mediterranean spotted fever patients of a new spotted fever group rickettsial strain (Bar29). Eur J Epidemiol 18: 351356.[Crossref]
  6. Vitale G, Mansueto S, Rolain JM, Raoult D, , 2006. Rickettsia massiliae human isolation. Emerg Infect Dis 12: 174175.[Crossref]
  7. Parola P, Socolovschi C, Jeanjean L, Bitam I, Fournier PE, Sotto A, Labauge P, Raoult D, , 2008. Warmer weather linked to tick attack and emergence of severe rickettsioses. PLoS Negl Trop Dis 2: e338.[Crossref]
  8. Regnery RL, Spruill CL, Plikaytis BD, , 1991. Genotypic identification of rickettsiae and estimation of intraspecies sequence divergence for portions of two rickettsial genes. J Bacteriol 173: 15761589.[Crossref]
  9. Choi YJ, Jang WJ, Ryu JS, Lee SH, Park KH, Paik HS, Koh YS, Choi MS, Kim IS, , 2005. Spotted fever group and typhus group rickettsioses in humans, South Korea. Emerg Infect Dis 11: 237244.[Crossref]
  10. Bernabeu-Wittel M, del Toro MD, Nogueras MM, Muniain MA, Cardeñosa N, Segura F, Pachon J, , 2006. Presence of human past infections due to the Bar29 rickettsial strain in southern Spain. J Infect 52: e117e119.[Crossref]

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  • Received : 04 Nov 2009
  • Accepted : 26 Dec 2009

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