Volume 83, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The aim of the present preliminary study was to investigate the potential of measurement of IFN-γ secretion by T cells into blood plasma using QuantiFERON assay with leishmanial antigens to determine the presence of infection. Blood samples from cured visceral ( = 18), and cutaneous ( = 20) leishmaniasis cases, and 20 healthy controls were tested. The IFN-γ responses to H2B and H2B antigens were detected from the majority of treated old visceral leishmaniasis cases, but not from controls. Future studies using larger groups will be required to establish the true potential of the assay for epidemiological screening of leishmaniasis.


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  • Received : 09 Oct 2009
  • Accepted : 03 May 2010
  • Published online : 05 Oct 2010
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