Volume 82, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



is the causative agent of visceral leishmaniasis in Brazil. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of kinetoplast DNA (kDNA) minicircles was used to evaluate genetic profiles of 48 strains from dog and human parasite cultures, fresh collected dog bone marrow aspirates, and from infected sand flies. Results revealed that heterogeneity in kDNA minicircles depends mostly on the source of the samples, with cultured parasites showing a high degree of homogeneity.


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  • Received : 06 Oct 2009
  • Accepted : 14 Jan 2010
  • Published online : 05 May 2010

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