Volume 82, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Despite being free of charge, treatment adherence to 7-day primaquine for the radical cure of was estimated at 62.2% among patients along the Iquitos-Nauta road in the Peruvian Amazon. The principal reason for non-adherence was the perceived adverse effects related to local humoral illness conceptions that hold that malaria produces a hot state of body, which is further aggravated by the characteristically hot medical treatment. Notably, patients were willing to adhere to the first 3 days of treatment during which symptoms are most apparent and include the characteristic chills. Nevertheless, as symptoms abate, the perceived aggravating characteristics of the medication outweigh the perceived advantages of treatment adherence. Improving community awareness about the role of primaquine to prevent further malaria transmission and fostering a realistic system of direct observed treatment intake, organized at community level, can be expected to improve adherence to the radical cure of in this area.


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  • Received : 04 Sep 2009
  • Accepted : 27 Nov 2009
  • Published online : 04 Jun 2010

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