1921
Volume 82, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

In this study we present, for the first time, a three-dimensional digital reconstruction of larval growth in human tissue. Formalin-fixed, paraffin-embedded hepatic tissues from patients with alveolar echinococcosis were serially sectioned, stained, and areas of larval growth of the parasite were microphotographed. Parasitic structures were reconstructed from multiple digital planes, revealing a root-like network of interconnected vesicles and tubules extending into the periphery of lesions.

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2010-01-01
2017-11-18
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References

  1. Rausch RL, Wilson JF, Schantz PM, McMahon BJ, , 1987. Spontaneous death of Echinococcus multilocularis: cases diagnosed serologically (by Em2 ELISA) and clinical significance. Am J Trop Med Hyg 36: 576585.
  2. Vogel H, , 1978. How does the alveolar echinococcus grow? [in German]. Tropenmed Parasitol 29: 111.
  3. Rausch R, , 1954. Studies on the helminth fauna of Alaska. XX. The histogenesis of the alveolar larva of Echinococcus species. J Infect Dis: 94 178186.[Crossref]
  4. Vogel H, , 1977. On Echinococcus multilocularis in southern Germany II. Development of the larval stages and histopathological reactions in common vole, Microtus arvalis [in German]. Tropenmed Parasitol: 28 409427.
  5. Eckert J, Thompson RC, Mehlhorn H, , 1983. Proliferation and metastases formation of larval Echinococcus multilocularis. I. Animal model, macroscopical and histological findings. Z Parasitenkd: 69 737748.[Crossref]
  6. Mehlhorn H, Eckert J, Thompson RC, , 1983. Proliferation and metastases formation of larval Echinococcus multilocularis. II. Ultrastructural investigations. Z Parasitenkd: 69 749763.[Crossref]
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  • Received : 10 Aug 2009
  • Accepted : 15 Sep 2009

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