1921
Volume 82, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

A seroprevalence study for IgG antibodies against spotted fever group (SFGR) and typhus group (TGR) among humans and domestic pets was conducted in the city of Iquitos, located in the Amazon basin of Peru. Of 1,195 human sera analyzed, 521 (43.6%) and 123 (10.3%) were positive for SFGR and TGR antibodies, respectively. District of residence and participant age were associated with antibody positivity for both groups, whereas rodent sightings in the home were associated with TGR antibody positivity. Of the 71 canines tested, 42 (59.2%) were positive for SFGR antibodies, and two (2.8%) were positive for TGR antibodies; one active SFGR infection was detected by polymerase chain reaction. An uncharacterized SFGR species was detected in 95.9% (71/74) of pools collected from domestic pets. These data suggest that rickettsial transmission is widespread in Iquitos. species should be further explored as potential causes of acute febrile illnesses in the region.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2010.09-0355
2010-04-01
2017-09-19
Loading full text...

Full text loading...

/deliver/fulltext/14761645/82/4/683.html?itemId=/content/journals/10.4269/ajtmh.2010.09-0355&mimeType=html&fmt=ahah

References

  1. Parola P, Paddock CD, Raoult D, , 2005. Tick-borne rickettsioses around the world: emerging diseases challenging old concepts. Clin Microbiol Rev 18: 719756.[Crossref]
  2. Parola P, Raoult D, , 2006. Tropical rickettsioses. Clin Dermatol 24: 191200.[Crossref]
  3. Perlman SJ, Hunter MS, Zchori-Fein E, , 2006. The emerging diversity of Rickettsia . Proc Biol Sci 273: 20972106.[Crossref]
  4. Galvao MA, Mafra CL, Moron C, Anaya E, Walker DH, , 2003. Rickettsiosis of the genus Rickettsia in South America. Ann NY Acad Sci 990: 5761.[Crossref]
  5. Lamas C, Favacho A, Rozental T, Boia MN, Kirsten AH, Guterres A, Barreira J, de Lemos ER, , 2008. Characterization of Rickettsia rickettsii in a case of fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil. Braz J Infect Dis 12: 149151.[Crossref]
  6. Angerami RN, Resende MR, Feltrin AF, Katz G, Nascimento EM, Stucchi RS, Silva LJ, , 2006. Brazilian spotted fever: a case series from an endemic area in southeastern Brazil: clinical aspects. Ann NY Acad Sci 1078: 252254.[Crossref]
  7. Angerami RN, Resende MR, Feltrin AF, Katz G, Nascimento EM, Stucchi RS, Silva LJ, , 2006. Brazilian spotted fever: a case series from an endemic area in southeastern Brazil: epidemiological aspects. Ann NY Acad Sci 1078: 170172.[Crossref]
  8. de Lemos ER, Alvarenga FB, Cintra ML, Ramos MC, Paddock CD, Ferebee TL, Zaki SR, Ferreira FC, Ravagnani RC, Machado RD, Guimaraes MA, Coura JR, , 2001. Spotted fever in Brazil: a seroepidemiological study and description of clinical cases in an endemic area in the state of Sao Paulo. Am J Trop Med Hyg 65: 329334.
  9. de Lemos ER, Machado RD, Coura JR, , 1994. Rocky Mountain spotted fever in an endemic area in Minas Gerais, Brazil. Mem Inst Oswaldo Cruz 89: 497501.[Crossref]
  10. Moraes-Filho J, Pinter A, Pacheco RC, Gutmann TB, Barbosa SO, Gonzales MA, Muraro MA, Cecilio SR, Labruna MB, , 2008. New epidemiological data on Brazilian spotted fever in an endemic area of the state of Sao Paulo, Brazil. Vector Borne Zoonotic Dis 9: 7378.[Crossref]
  11. Rozental T, Bustamante MC, Amorim M, Serra-Freire NM, Lemos ER, , 2002. Evidence of spotted fever group rickettsiae in state of Rio de Janeiro, Brazil. Rev Inst Med Trop Sao Paulo 44: 155158.[Crossref]
  12. Vianna MC, Horta MC, Sangioni LA, Cortez A, Soares RM, Mafra CL, Galvao MA, Labruna MB, Gennari SM, , 2008. Rickettsial spotted fever in capoeirao village, Itabira, Minas Gerais, Brazil. Rev Inst Med Trop Sao Paulo 50: 297301.[Crossref]
  13. Hidalgo M, Orejuela L, Fuya P, Carrillo P, Hernandez J, Parra E, Keng C, Small M, Olano JP, Bouyer D, Castaneda E, Walker D, Valbuena G, , 2007. Rocky Mountain spotted fever, Colombia. Emerg Infect Dis 13: 10581060.[Crossref]
  14. Paddock CD, Fernandez S, Echenique GA, Sumner JW, Reeves WK, Zaki SR, Remondegui CE, , 2008. Rocky Mountain spotted fever in Argentina. Am J Trop Med Hyg 78: 687692.
  15. Venzal JM, Perez-Martinez L, Felix ML, Portillo A, Blanco JR, Oteo JA, , 2006. Prevalence of Rickettsia felis in Ctenocephalides felis and Ctenocephalides canis from Uruguay. Ann NY Acad Sci 1078: 305308.[Crossref]
  16. Pacheco RC, Venzal JM, Richtzenhain LJ, Labruna MB, , 2006. Rickettsia parkeri in Uruguay. Emerg Infect Dis 12: 18041805.[Crossref]
  17. Nava S, Perez-Martinez L, Venzal JM, Portillo A, Santibanez S, Oteo JA, , 2008. Rickettsia felis in Ctenocephalides felis from Argentina. Vector Borne Zoonotic Dis 8: 465466.[Crossref]
  18. Gehrke FS, Gazeta GS, Souza ER, Ribeiro A, Marrelli MT, Schumaker TT, , 2009. Rickettsia rickettsii, Rickettsia felis and Rickettsia sp. TwKM03 infecting Rhipicephalus sanguineus and Ctenocephalides felis collected from dogs in a Brazilian spotted fever focus in the state of Rio De Janeiro/Brazil. Clin Microbiol Infect 15: 267268.[Crossref]
  19. Hidalgo M, Sanchez R, Orejuela L, Hernandez J, Walker DH, Valbuena G, , 2007. Prevalence of antibodies against spotted fever group rickettsiae in a rural area of Colombia. Am J Trop Med Hyg 77: 378380.
  20. Blair PJ, Schoeler GB, Moron C, Anaya E, Caceda R, Cespedes M, Cruz C, Felices V, Guevara C, Huaman A, Luckett R, Mendoza L, Richards AL, Rios Z, Sumner JW, Villaseca P, Olson JG, , 2004. Evidence of rickettsial and leptospira infections in Andean northern Peru. Am J Trop Med Hyg 70: 357363.
  21. Schoeler GB, Moron C, Richards A, Blair PJ, Olson JG, , 2005. Human spotted fever rickettsial infections. Emerg Infect Dis 11: 622624.[Crossref]
  22. Sihuincha MM, Anaya FE, Carranza VV, Durand VS, , 2006. Serological evidence of spotted fever group-related Rickettsia transmission in the Peruvian Amazon jungle. Rev Perú Med Exp Salud Publica 23: 284287.
  23. Ramal AC, Díaz DE, López TJ, , 2007. Rickettsiosis, emerging disease in Loreto. Rev Perú Med Exp Salud Publica 24: 99100.
  24. Morrison AC, Forshey BM, Notyce D, Astete H, Lopez V, Rocha C, Carrion R, Carey C, Eza D, Montgomery JM, Kochel TJ, , 2008. Venezuelan equine encephalitis virus in Iquitos, Peru: urban transmission of a sylvatic strain. PLoS Negl Trop Dis 2: e349.[Crossref]
  25. Morrison AC, Astete H, Chapilliquen F, Ramirez-Prada C, Diaz G, Getis A, Gray K, Scott TW, , 2004. Evaluation of a sampling methodology for rapid assessment of Aedes aegypti infestation levels in Iquitos, Peru. J Med Entomol 41: 502510.[Crossref]
  26. Morrison AC, Gray K, Getis A, Astete H, Sihuincha M, Focks D, Watts D, Stancil JD, Olson JG, Blair P, Scott TW, , 2004. Temporal and geographic patterns of Aedes aegypti (Diptera: Culicidae) production in Iquitos, Peru. J Med Entomol 41: 11231142.[Crossref]
  27. Getis A, Morrison AC, Gray K, Scott TW, , 2003. Characteristics of the spatial pattern of the dengue vector, Aedes aegypti, in Iquitos, Peru. Am J Trop Med Hyg 69: 494505.
  28. Chao CC, Zhang Z, Wang H, Alkhalil A, Ching WM, , 2008. Serological reactivity and biochemical characterization of methylated and unmethylated forms of a recombinant protein fragment derived from outer membrane protein B of Rickettsia typhi . Clin Vaccine Immunol 15: 684690.[Crossref]
  29. Blair PJ, Jiang J, Schoeler GB, Moron C, Anaya E, Cespedes M, Cruz C, Felices V, Guevara C, Mendoza L, Villaseca P, Sumner JW, Richards AL, Olson JG, , 2004. Characterization of spotted fever group rickettsiae in flea and tick specimens from northern Peru. J Clin Microbiol 42: 49614967.[Crossref]
  30. Reeves WK, Nelder MP, Korecki JA, , 2005. Bartonella and Rickettsia in fleas and lice from mammals in South Carolina, USA. J Vector Ecol 30: 310315.
  31. Loftis AD, Reeves WK, Szumlas DE, Abbassy MM, Helmy IM, Moriarity JR, Dasch GA, , 2006. Surveillance of Egyptian fleas for agents of public health significance: Anaplasma, Bartonella, Coxiella, Ehrlichia, Rickettsia, and Yersinia pestis . Am J Trop Med Hyg 75: 4148.
  32. Parola P, Cornet JP, Sanogo YO, Miller RS, Thien HV, Gonzalez JP, Raoult D, Telford IS, Wongsrichanalai C, , 2003. Detection of Ehrlichia spp., Anaplasma spp., Rickettsia spp., and other eubacteria in ticks from the Thai-Myanmar border and Vietnam. J Clin Microbiol 41: 16001608.[Crossref]
  33. Parola P, Sanogo OY, Lerdthusnee K, Zeaiter Z, Chauvancy G, Gonzalez JP, Miller RS, Telford SR, 3rd Wongsrichanalai C, Raoult D, , 2003. Identification of Rickettsia spp. and Bartonella spp. from the Thai-Myanmar border. Ann NY Acad Sci 990: 173181.[Crossref]
  34. Raoult D, Birtles RJ, Montoya M, Perez E, Tissot-Dupont H, Roux V, Guerra H, , 1999. Survey of three bacterial louse-associated diseases among rural Andean communities in Peru: prevalence of epidemic typhus, trench fever, and relapsing fever. Clin Infect Dis 29: 434436.[Crossref]
  35. da Costa PS, Brigatte ME, Greco DB, , 2005. Antibodies to Rickettsia rickettsii, Rickettsia typhi, Coxiella burnetii, Bartonella henselae, Bartonella quintana, and Ehrlichia chaffeensis among healthy population in Minas Gerais, Brazil. Mem Inst Oswaldo Cruz 100: 853859.[Crossref]
  36. Pinter A, Horta MC, Pacheco RC, Moraes-Filho J, Labruna MB, , 2008. Serosurvey of Rickettsia spp. in dogs and humans from an endemic area for Brazilian spotted fever in the State of Sao Paulo, Brazil. Cad Saude Publica 24: 247252.[Crossref]
  37. Horta MC, Labruna MB, Sangioni LA, Vianna MC, Gennari SM, Galvao MA, Mafra CL, Vidotto O, Schumaker TT, Walker DH, , 2004. Prevalence of antibodies to spotted fever group rickettsiae in humans and domestic animals in a Brazilian spotted fever-endemic area in the state of Sao Paulo, Brazil: serologic evidence for infection by Rickettsia rickettsii and another spotted fever group Rickettsia . Am J Trop Med Hyg 71: 9397.
  38. Ripoll CM, Remondegui CE, Ordonez G, Arazamendi R, Fusaro H, Hyman MJ, Paddock CD, Zaki SR, Olson JG, Santos-Buch CA, , 1999. Evidence of rickettsial spotted fever and ehrlichial infections in a subtropical territory of Jujuy, Argentina. Am J Trop Med Hyg 61: 350354.
  39. Labruna MB, Kamakura O, Moraes-Filho J, Horta MC, Pacheco RC, , 2009. Rocky Mountain spotted fever in dogs, Brazil. Emerg Infect Dis 15: 458460.[Crossref]
  40. Elchos BN, Goddard J, , 2003. Implications of presumptive fatal Rocky Mountain spotted fever in two dogs and their owner. J Am Vet Med Assoc 223: 14501452, 1433.[Crossref]
  41. Paddock CD, Brenner O, Vaid C, Boyd DB, Berg JM, Joseph RJ, Zaki SR, Childs JE, , 2002. Short report: concurrent Rocky Mountain spotted fever in a dog and its owner. Am J Trop Med Hyg 66: 197199.
  42. Oliveira KA, Oliveira LS, Dias CC, Silva A, Jr Almeida MR, Almada G, Bouyer DH, Galvao MA, Mafra C, , 2008. Molecular identification of Rickettsia felis in ticks and fleas from an endemic area for Brazilian Spotted Fever. Mem Inst Oswaldo Cruz 103: 191194.[Crossref]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2010.09-0355
Loading
/content/journals/10.4269/ajtmh.2010.09-0355
Loading

Data & Media loading...

  • Received : 23 Jun 2009
  • Accepted : 21 Nov 2009

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error