Volume 82, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



After an outbreak of Chikungunya infection in Emilia-Romagna Region (North-eastern Italy), a survey was performed to estimate the seroprevalence of antibody to Chikungunya virus and the proportion of asymptomatic infections, to identify factors associated with infection, and evaluate the performance of the surveillance system. The method used was a survey on a random sample of residents of the village with the largest number of reported cases. The prevalence was 10.2% (33 of 325), being higher in older people and males, and lower when window screens and insect repellents were used. Only 18% of infected persons were fully asymptomatic, 85% of the 27 symptomatic confirmed cases satisfied the surveillance case definition, and 63% of the persons meeting the criteria for suspect case were identified by the active surveillance system. This study provides basic parameters for modeling the transmission potential of outbreaks and planning control measures for Chikungunya infection in temperate settings.


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  1. Pialoux G, Gauzere BA, Jaureguiberry S, Strobel M, 2007. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis 7: 319327.[Crossref]
    [Google Scholar]
  2. Rezza G, Nicoletti L, Angelini R, Romi R, Finarelli AC, Panning M, Cordioli P, Fortuna C, Boros S, Magurano F, Silvi G, Angelini P, Dottori M, Ciufolini MG, Majori GC, Cassone A, CHIKV study group, 2007. Infection with Chikungunya virus in Italy: an outbreak in a temperate region. Lancet 370: 18401846.[Crossref]
    [Google Scholar]
  3. Romi R, Di Luca M, Majori G, 1999. Current status of Aedes albopictus and Aedes atropalpus in Italy. J Am Mosq Control Assoc 15: 425427.
    [Google Scholar]
  4. Litzba N, Schuffenecker I, Zeller H, Drosten C, Emmerich P, Charrel R, Kreher P, Niedrig M, 2008. Evaluation of the first commercial Chikungunya virus indirect immunofluorescence test. J Virol Methods 149: 175179.[Crossref]
    [Google Scholar]
  5. Gérardin P, Perrau J, Fianu A, Favier F, 2008. Determinants of Chikungunya virus infection in the Reunion Island: results of the SEROCHIK seroprevalence survey in the population, August–October 2006. Bull Epidemiol Hebd 38-39-40: 361363.
    [Google Scholar]
  6. Sissoko D, Moendandze A, Malvy D, Giry C, Ezzedine K, Solet JL, Pierre V, 2008. Seroprevalence and risk factors of Chikungunya virus infection in Mayotte, Indian Ocean, 2005–2006: a population-based survey. PLoS One 3: e3066.[Crossref]
    [Google Scholar]
  7. Rizzo C, Poletti P, Ajelli M, Seyler T, Pugliese A, Salmaso S, Merler S. Investigating the transmission potential and the impact of control measures of the 2007 Chikungunja fever outbreak in Italy. In: Abstracts of the 2008 European Scientific Conference on Applied Infectious Disease Epidemiology (ESCAIDE). Berlin, Germany, November 19–21, 2008. Abstract: 20080187.
    [Google Scholar]
  8. Renault P, Solet JL, Sissoko D, Balleydier E, Larrieu S, Filleul L, Lassalle C, Thiria J, Rachou E, de Valk H, Ilef D, Ledrans M, Quatresous I, Quenel P, Pierre V, 2007. A major epidemic of Chikungunya virus infection on Reunion Island, France, 2005–2006. Am J Trop Med Hyg 77: 727731.
    [Google Scholar]
  9. Boëlle PY, Thomas G, Vergu E, Renault P, Valleron AJ, Flahault A, 2008. Investigating transmission in a two-wave epidemic of Chikungunya fever, Réunion Island. Vector Borne Zoonotic Dis 8: 207217.[Crossref]
    [Google Scholar]
  10. Renault P, Siisoko D, Ledrans M, Pierre V, Brucker G, 2008. Chikungunya outbreak on the Reunion Island and Mayotte, France, 2005–2006: context and questions raised for surveillance and evaluation. Bull Epidemiol Hebd 38-39-40: 343.
    [Google Scholar]

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  • Received : 12 Jun 2009
  • Accepted : 24 Nov 2009
  • Published online : 05 Mar 2010
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