Volume 82, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Rubella vaccination in Taiwan started in 1986; mass vaccination was introduced into the national immunization program in 1992. In recent years, 17–31% of all marriages in Taiwan have been between Taiwanese men and foreign women. The aim of this study was to analyze rubella seroepidemiology and the rate of catch-up immunization in women. We recruited 10,089 pregnant women, including 1,920 immigrants, who had received prenatal examinations during 1999–2006. The rates of seronegativity among global, Taiwan-born, and non–Taiwan-born pregnant women were 14.0%, 11.9%, and 23.1%, respectively. The seronegativity of rubella antibodies decreased from 28.2% for Taiwan-born women born before September 1971 to 8.0% for those born thereafter. The rates of rubella catch-up immunization among global, Taiwan-born, and non–Taiwan-born pregnant women were 28.6%, 20.5%, and 42.2%, respectively. Our results suggest that substantial numbers of older Taiwan-born women and immigrant women remain susceptible to rubella infection.


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  • Received : 02 Jun 2009
  • Accepted : 28 Sep 2009
  • Published online : 05 Jan 2010

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