Volume 82, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Chagas' disease, or American trypanosomiasis, is caused by the protozoan parasite . It is estimated that 15,000 new cases of congenital transmission occur in the Americas each year. The aim of this study was to estimate the rate of congenital infection in infants born to infected women living in Ushuaia, Argentina, as well to assess a serologic test using Shed Acute Phase Antigen (SAPA) for a timely diagnosis of congenital infection. The rate of congenital infection among children in the study was 4.4% (3/68). Our results show that for infants younger than 30 days of age, matched blood samples from mother and infant were capable of identifying congenital transmission of infection using an enzyme-linked immunosorbent assay with SAPA. For infants older than 3 months, congenital infection could be ruled out using the same procedure.


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  • Received : 27 Apr 2009
  • Accepted : 30 Jul 2009
  • Published online : 05 Jan 2010

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