1921
Volume 82, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

A cross-sectional study was carried out in Água Comprida, MG, Brazil, a region previously endemic to Chagas disease whose vectorial transmission was interrupted around 20 year ago. A total of 998 individuals were examined for anti- antibodies. Seropositivity was observed in 255 subjects (25.5%), and 743 subjects were negative. Forty-one families with 5–80 individuals with similar environmental conditions were selected for familial analysis. In 15 families, seropositivity to was observed in > 50% of individuals. The segregation analysis confirmed family aggregation for the seropositivity to the . Heart commitment was the major clinical form observed, and in six families, > 50% of the individuals display cardiopathy that may be attributed to infection. Our results support the hypothesis that there is a family aggregation for the seropositivity but without the effect of one major gene.

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2017-11-20
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  • Received : 02 Dec 2009
  • Accepted : 28 Sep 2009

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