Volume 81, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


We previously developed a real-time polymerase chain reaction (PCR) assay for detection of the four species that infect humans. Recent studies have shown that natural transmission of the simian parasite to humans occurs frequently in Southeast Asia. We have expanded our PCR assay to include detection of .


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Cox-Singh J, Davis TM, Lee KS, Shamsul SS, Matusop A, Ratnam S, Rahman HA, Conway DJ, Singh B, 2008. Plasmodium knowlesi malaria in humans is widely distributed and potentially life threatening. Clin Infect Dis 46 : 165–171. [Google Scholar]
  2. Singh B, Kim Sung L, Matusop A, Radhakrishnan A, Shamsul SS, Cox-Singh J, Thomas A, Conway DJ, 2004. A large focus of naturally acquired Plasmodium knowlesi infections in human beings. Lancet 363 : 1017–1024. [Google Scholar]
  3. White NJ, 2008. Plasmodium knowlesi: the fifth human malaria parasite. Clin Infect Dis 46 : 172–173. [Google Scholar]
  4. Swan H, Sloan L, Muyombwe A, Chavalitshewinkoon-Petmitr P, Krudsood S, Leowattana W, Wilairatana P, Looareesuwan S, Rosenblatt J, 2005. Evaluation of a real-time polymerase chain reaction assay for the diagnosis of malaria in patients from Thailand. Am J Trop Med Hyg 73 : 850–854. [Google Scholar]
  5. Fong YL, Cadigan FC, Coatney GR, 1971. A presumptive case of naturally occurring Plasmodium knowlesi malaria in man in Malaysia. Trans R Soc Trop Med Hyg 65 : 839–840. [Google Scholar]
  6. Jongwutiwes S, Putaporntip C, Iwasaki T, Sata T, Kanbara H, 2004. Naturally acquired Plasmodium knowlesi malaria in human, Thailand. Emerg Infect Dis 10 : 2211–2213. [Google Scholar]
  7. Luchavez J, Espino F, Curameng P, Espina R, Bell D, Chiodini P, Nolder D, Sutherland C, Lee KS, Singh B, 2008. Human Infections with Plasmodium knowlesi, the Philippines. Emerg Infect Dis 14 : 811–813. [Google Scholar]
  8. Ng OT, Ooi EE, Lee CC, Lee PJ, Ng LC, Pei SW, Tu TM, Loh JP, Leo YS, 2008. Naturally acquired human Plasmodium knowlesi infection, Singapore. Emerg Infect Dis 14 : 814–816. [Google Scholar]
  9. Vythilingam I, Tan CH, Asmad M, Chan ST, Lee KS, Singh B, 2006. Natural transmission of Plasmodium knowlesi to humans by Anopheles latens in Sarawak, Malaysia. Trans R Soc Trop Med Hyg 100 : 1087–1088. [Google Scholar]
  10. Gushulak BD, MacPherson DW, 2004. Globalization of infectious diseases: the impact of migration. Clin Infect Dis 38 : 1742–1748. [Google Scholar]

Data & Media loading...

  • Received : 15 Jan 2009
  • Accepted : 08 Jun 2009

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error