1921
Volume 81, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Non-specific lymphocytic myocarditis (NLM) is frequently observed in baboons within the endemic range of . We sought to determine whether infection is a cause of baboon NLM. We evaluated serial histologic sections of cardiac muscle, blood cultures, immunohistochemistry, serology, polymerase chain reaction, and clinical pathology from 31 baboons with NLM to determine whether infection is associated with NLM. Eleven baboons with no evidence of infection by serology and no NLM were used as controls. Seropositivity for was 45% in baboons with NLM compared with a 2–3% colony prevalence. NLM lesion severity was significantly higher in seropositive than seronegative baboons with NLM. NLM was significantly more common in older baboons. No statistical association between NLM and sex, weight, or clinical pathology was found. These results suggest an association between NLM and infection in the baboon.

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2009-08-01
2017-11-22
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  • Received : 01 Apr 2009
  • Accepted : 23 May 2009

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