1921
Volume 81, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Cutaneous leishmaniasis (CL) is prevalent in the Egyptian Sinai Peninsula and previous research has consistently documented the etiologic agent to be . We report the first isolation of from human cases of CL in a Northern Sinai community bordering Palestine. Parasite culturing, real-time polymerase chain reaction (PCR), gene sequencing, and restriction fragment length polymorphism (RFLP) analyses indicate CL cases in this community were caused by either or (three cases each). Two wild-caught rodents () were infected with sand flies were found harboring , however only non-infected individuals of , a vector for were caught. Patients with had not traveled from the region in over a year, suggesting these cases are autochthonous. This scenario is consistent with an incursion of from bordering countries and raises concerns about expansion of this parasite further into Egypt.

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  • Received : 25 Jan 2009
  • Accepted : 31 Mar 2009

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