Volume 81, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Inappropriate antimicrobial drug use is well described for hospitalized patients in the United States. Antibiotic use in hospitals in developing countries is less well documented. We evaluated the antibiotics prescribed to 91 pediatric inpatients in Botswana. The results showed that the duration of prescribed therapy can be excessive. Recommendations for potential interventions to reduce antibiotic overuse in this setting are necessary.


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  1. Davey P, Garner S, 2007. Professional education on antimicrobial prescribing: a report from the Specialist Advisory Committee on Antimicrobial Resistance (SACAR) Professional Education Subgroup. J Antimicrob Chemother 60 (Suppl 1) : i27–i32.
    [Google Scholar]
  2. Scheckler WE, Bennett JV, 1970. Antibiotic usage in seven community hospitals. JAMA 213 : 264–267.
    [Google Scholar]
  3. Huebner RE, Wasas A, Mushi A, Mazhani L, Klugman K, 1998. Nasopharyngeal carriage and antimicrobial resistance in isolates of Streptococcus pneumoniae and Haemophilus influenzae type b in children under 5 years of age in Botswana. Int J Infect Dis 3 : 18–25.
    [Google Scholar]
  4. Urio EM, Collison EK, Gashe BA, Sebunya TK, Mpuchane S, 2001. Shigella and Salmonella strains isolated from children under 5 years in Gaborone, Botswana, and their antibiotic susceptibility patterns. Trop Med Int Health 6 : 55–59.
    [Google Scholar]
  5. World Health Organization, 2008. Core Health Indicators 2008. Available at: http://www.who.int/whosis/database/core/core_select.cfm?strISO3_select=afg&strIndicator_select=BirthsAttended&intYear_select=latest&language=english. Accessed December 3, 2008.
  6. UNICEF, World Health Organization, 1998. Pneumonia: The Forgotten Killer of Children. New York: UNICEF and World Health Organization.
  7. Neuzil KM, Mellen BG, Wright PF, Mitchel EF Jr, Griffin MR, 2000. The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children. N Engl J Med 342 : 225–231.
    [Google Scholar]
  8. Shah SS, Downes KJ, Elliott MR, Bell LM, McGowan KL, Metlay JP, 2008. How long does it take to “rule out” bacteremia in children with central venous catheters? Pediatrics 121 : 135–141.
    [Google Scholar]
  9. Boonstra E, Lindbaek M, Ngome E, 2005. Adherence to management guidelines in acute respiratory infections and diarrhoea in children under 5 years old in primary health care in Botswana. Int J Qual Health Care 17 : 221–227.
    [Google Scholar]

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  • Received : 04 Dec 2008
  • Accepted : 11 Feb 2009
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