1921
Volume 80, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

An investigation into the risk of occupationally acquired melioidosis at a mine site in northern Australia found that 45 (13%) of 345 staff had serologic evidence of exposure and 14 (4%) had recent exposure to or closely related bacteria. There was only one culture-confirmed case of melioidosis in mine staff during the study period. The lack of overt infection directly attributable to work activities despite detectable on site, the absence of an association between positive serology and occupational activity on site, or duration of employment in the mining industry stand against a significant occupationally acquired infection risk on this industrial site. Workplace exposure to a dust-generating tropical environment in the melioidosis-endemic north of Australia did not appear to pose a measurable increase in infection risk. The effect of long-term climatic trends on this potential biologic threat requires further study.

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2009-01-01
2017-09-20
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References

  1. Cheng AC, Currie BJ, 2005. Melioidosis: epidemiology, pathophysiology, and management. Clin Microbiol Rev 18 : 383–416.
  2. Currie BJ, Jacups SP, Cheng AC, Fisher DA, Anstey NM, Huffam SE, Krause VL, 2004. Melioidosis epidemiology and risk factors from a prospective whole-population study in northern Australia. Trop Med Int Health 9 : 1167–1174.
  3. Inglis TJ, Garrow SC, Adams C, Henderson M, Mayo M, 1998. Dry-season outbreak of melioidosis in Western Australia. Lancet 352 : 1600.
  4. Inglis TJ, Rolim DB, Rodriguez JL, 2006. Clinical guideline for diagnosis and management of melioidosis. Rev Inst Med Trop São Paulo 48 : 1–4.
  5. Levy A, Merritt AJ, Aravena-Roman M, Hodge MM, Inglis TJJ, 2008. Expanded range of Burkholderia species in Australia. Am J Trop Med Hyg 78 : 599–604.
  6. Merritt A, Inglis TJ, Chidlow G, Harnett G, 2006. PCR-based identification of Burkholderia pseudomallei. Rev Inst Med Trop S Paulo 48 : 239–244.
  7. Payne GW, Vandamme P, Morgan SH, Lipuma JJ, Coenye T, Weightman AJ, Jones TH, Mahenthiralingam E, 2005. Development of a recA gene-based identification approach for the entire Burkholderia genus. Appl Environ Microbiol 71 : 3917–3927.
  8. Inglis TJ, O’Reilly L, Foster N, Clair A, Sampson J, 2002. Comparison of rapid automated ribotyping and DNA macrorestriction analysis of Burkholderia pseudomallei. J Clin Microbiol 40 : 3198–3203.
  9. Warawa J, Woods DE, 2002. Melioidosis vaccines. Expert Rev Vaccines 1 : 477–482.
  10. Inglis TJ, Garrow SC, Henderson M, Clair A, Sampson J, O’Reilly L, Cameron B, 2000. Burkholderia pseudomallei traced to water treatment plant in Australia. Emerg Infect Dis 6 : 56–59.
  11. Communicable Disease Control Directorate, 2008. Statewide Notifiable Diseases Weekly Report. Department of Health, Government of Western Australia. 06-MAY-08 to 30-JUN-08, 2.
  12. Rosario K, Iverson SL, Henderson DA, Chartrand S, McKeon C, Glenn EP, Maier RM, 2007. Bacterial community changes during plant establishment at the San Pedro river mine tailings site. J Environ Qual 36 : 1249–1259.
  13. Currie BJ, Jacups SP, 2003. Intensity of rainfall and severity of melioidosis, Australia. Emerg Infect Dis 9 : 1538–1542.
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  • Received : 16 Jul 2008
  • Accepted : 16 Aug 2008

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