Volume 80, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Fifty-one published studies of travelers’ diarrhea (TD) were examined to look for regional differences in pathogens identified. Enterotoxigenic was detected in 1,678/5,518 (30.4%) of TD cases overall, with rates in Latin America/Caribbean (L. America), Africa, south Asia, and Southeast Asia of 1,109/3,302 (33.6%), 389/1,217 (31.2%), 153/499 (30.6%), and 36/500 (7.2%), respectively ( < 0.001). Enteroaggregative was the second most common agent in L. America, found in 166/689 (24.1%), compared with 3/165 (1.8%) in Africa and 33/206 (16%) in south Asia ( < 0.001). Other significantly regional differences were seen for enteropathogenic , diffusely adherent , , spp., , spp., , , rotavirus, noroviruses, and . The regional differences in pathogen identification identified will serve as a baseline for antimicrobial therapy recommendations and vaccines strategies.


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  • Received : 03 Oct 2008
  • Accepted : 20 Dec 2008

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