1921
Volume 80, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

The agent of Chagas disease, , is phylogenetically divided into two lineages, I (TCI) and II (TCII). TCI is found in sylvatic and domestic habitats across South America. Despite a high prevalence of TCII in domestic habitats in South America, it has been rarely found in domestic habitats in Central America and Mexico. This may be caused by limitations in detection tests previously used. A modified hemi-nested polymerase chain reaction assay was developed to improve detection of TCI and TCII mini-exon genes. This method detected TCI and II concurrently in 84% of 44 cultured isolates from specimens collected inside homes across the disease-endemic area in Guatemala.

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2009-02-01
2017-09-20
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References

  1. Barnabé C, Brisse S, Tibayrenc M, 2000. Population structure and genetic typing of Trypanosoma cruzi, the agent of Chagas disease: a multilocus enzyme electrophoresis approach. Parasitology 120 : 513–526.
  2. Kawashita SY, Sanson GF, Fernandes O, Zingales B, Briones MR, 2001. Maximum-likelihood divergence date estimates based on rRNA gene sequences suggest two scenarios of Trypanosoma cruzi intraspecific evolution. Mol Biol Evol 18 : 2250–2259.
  3. Zingales B, Stolf BS, Souto RP, Fernandes O, Briones MR, 1999. Epidemiology, biochemistry and evolution of Trypanosoma cruzi lineages based on ribosomal RNA sequences. Mem Inst Oswaldo Cruz 94 (Suppl 1) : 159–164.
  4. Briones MR, Souto RP, Stolf BS, Zingales B, 1999. The evolution of two Trypanosoma cruzi subgroups inferred from rRNA genes can be correlated with the interchange of American mammalian faunas in the Cenozoic and has implications to pathogenicity and host specificity. Mol Biochem Parasitol 104 : 219–232.
  5. Fernandes O, Souto RP, Castro JA, Borges Pereira J, Carrara Fernandes N, Junqueira ACV, Naiff RD, Barrett TV, Degrave W, Zingales B, Campbell DA, Coura JR, 1998. Brazilian isolates of Trypanosoma cruzi from humans and triatomines classified into two lineages using mini-exon and ribosomal RNA sequences. Am J Trop Med Hyg 58 : 807–811.
  6. Barnabé C, Neubauer K, Solari A, Tibayrenc M, 2001. Trypanosoma cruzi: presence of the two major phylogenetic and several lesser discrete typing units (DTUs) in Chile. Acta Trop 78 : 127–137.
  7. Brisse S, Barnabé C, Tibayrenc M, 2000. Identification of six Trypanosoma cruzi phylogenetic lineages by random amplified polymorphic DNA and multilocus enzyme electrophoresis. Int J Parasitol 30 : 35–44.
  8. Brisse S, Verhoef J, Tibayrenc M, 2001. Characterisation of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages. Int J Parasitol 31 : 1218–1226.
  9. Westenberger SJ, Sturm NR, Campbell DA, 2006. Trypanosoma cruzi 5S rRNA arrays define five groups and indicate the geographic origins of an ancestor of the heterozygous hybrids. Int J Parasitol 36 : 337–346.
  10. Yeo M, Acosta N, Llewellyn M, Sanchez H, Adamson S, Miles GA, Lopez E, Gonzalez N, Patterson JS, Gaunt MW, de Arias AR, Miles MA, 2005. Origins of Chagas disease: Didelphis species are natural hosts of Trypanosoma cruzi I and armadillos hosts of Trypanosoma cruzi II, including hybrids. Int J Parasitol 35 : 225–233.
  11. Anez N, Crisante G, da Silva FM, Rojas A, Carrasco H, Umezawa ES, Stolf AM, Ramirez JL, Teixeira MM, 2004. Predominance of lineage I among Trypanosoma cruzi isolates from Venezuelan patients with different clinical profiles of acute Chagas’ disease. Trop Med Int Health 9 : 1319–1326.
  12. Di Noia JM, Buscaglia CA, De Marchi CR, Almeida IC, Frasch AC, 2002. A Trypanosoma cruzi small surface molecule provides the first immunological evidence that Chagas’ disease is due to a single parasite lineage. J Exp Med 195 : 401–413.
  13. Yabsley MJ, Noblet GP, 2002. Biological and molecular characterization of a raccoon isolate of Trypanosoma cruzi from South Carolina. J Parasitol 88 : 1273–1276.
  14. Clark CG, Pung OJ, 1994. Host specificity of ribosomal DNA variation in sylvatic Trypanosoma cruzi from North America. Mol Biochem Parasitol 66 : 175–179.
  15. Higo H, Miura S, Horio M, Mimori T, Hamano S, Agatsuma T, Yanagi T, Cruz-Reyes A, Uyema N, Rojas de Arias A, Matta V, Akahane H, Hirayama K, Takeuchi T, Tada I, Himeno K, 2004. Genotypic variation among lineages of Trypanosoma cruzi and its geographic aspects. Parasitol Int 53 : 337–344.
  16. Cardinal MV, Lauricella MA, Ceballos LA, Lanati L, Marcet PL, Levin MJ, Kitron U, Gürtler RE, Schijman AG, 2008. Molecular epidemiology of domestic and sylvatic Trypanosoma cruzi infection in rural northwestern Argentina. Int J Parasitol Doi: 10.1016/j.ijpara.2008.04.010. Accessed September 3, 2008.
  17. Virreira M, Serrano G, Maldonado L, Svoboda M, 2006. Trypanosoma cruzi: typing of genotype (sub) lineages in megacolon samples from bolivian patients. Acta Trop 100 : 252–255.
  18. Burgos JM, Altcheh J, Bisio M, Duffy T, Valadares HM, Seidenstein ME, Piccinali R, Freitas JM, Levin MJ, Macchi L, Macedo AM, Freilij H, Schijman AG, 2007. Direct molecular profiling of minicircle signatures and lineages of Trypanosoma cruzi bloodstream populations causing congenital Chagas disease. Int J Parasitol 37 : 1319–1327.
  19. Marcet PL, Duffy T, Cardinal MV, Burgos JM, Lauricella MA, Levin MJ, Kitron U, Gürtler RE, Schijman AG, 2006. PCR-based screening and lineage identification of Trypanosoma cruzi directly from faecal samples of triatomine bugs from northwestern Argentina. Parasitology 132 : 57–65.
  20. Ruiz-Sanchez R, Leon MP, Matta V, Reyes PA, Lopez R, Jay D, Monteon VM, 2005. Trypanosoma cruzi isolates from Mexican and Guatemalan acute and chronic chagasic cardiopathy patients belong to Trypanosoma cruzi I. Mem Inst Oswaldo Cruz 100 : 281–283.
  21. Brenière SF, Bosseno MF, Magallon-Gastelum E, Castillo Ruvalcaba EG, Gutierrez MS, Montano Luna EC, Basulto JT, Mathieu-Daude F, Walter A, Lozano-Kasten F, 2007. Peridomestic colonization of Triatoma longipennis (Hemiptera, Reduviidae) and Triatoma barberi (Hemiptera, Reduviidae) in a rural community with active transmission of Trypanosoma cruzi in jalisco state, Mexico. Acta Trop 101 : 249–257.
  22. Samudio F, Ortega-Barria E, Saldana A, Calzada J, 2007. Predominance of Trypanosoma cruzi I among Panamanian sylvatic isolates. Acta Trop 101 : 178–181.
  23. Higo H, Miura S, Agatsuma T, Mimori T, Yanagi T, Iwagami M, de Arias AR, Matta V, Hirayama K, Takeuchi T, Tada I, Himeno K, 2007. Identification of Trypanosoma cruzi sublineages by the simple method of single-stranded conformation DNA polymorphism (SSCP). Parasitol Res 100 : 1023–1031.
  24. Sousa OE, Samudio F, de Junca C, Calzada JE, 2006. Molecular characterization of human Trypanosoma cruzi isolates from endemic areas in Panama. Mem Inst Oswaldo Cruz 101 : 455–457.
  25. Bosseno MF, Barnabé C, Magallon Gastelum E, Lozano Kasten F, Ramsey J, Espinoza B, Brenière SF, 2002. Predominance of Trypanosoma cruzi lineage I in Mexico. J Clin Microbiol 40 : 627–632.
  26. Bosseno MF, García LS, Baunaure F, Magallón E, Soto M, Lozano F, Dumonteil E, Brenière S, 2006. Shot report: identification in triatomine vectors of feeding sources and Trypanosoma cruzi variants by heteroduplex assay and multiplex mini-exon polymerase chain reaction. Am J Trop Med Hyg 74 : 303–305.
  27. Souto RP, Fernandes O, Macedo AM, Campbell DA, Zingales B, 1996. DNA markers define two major phylogenetic lineages of Trypanosoma cruzi. Mol Biochem Parasitol 83 : 141–152.
  28. Fernandes O, Santos SS, Cupolillo E, Mendoça B, Derre R, Junqueira ACV, Santos LC, Sturm NR, Naiff RD, Barret TV, Campbell DA, Coura JR, 2001. A mini-exon multiplex poly-merase chain reaction to distinguish the major groups of Trypanosoma cruzi and T. rangeli in the Brazilian Amazon. Trans R Soc Trop Med Hyg 95 : 97–99.
  29. O’Connor O, Bosseno MF, Barnabé C, Douzery EJ, Brenière SF, 2007. Genetic clustering of Trypanosoma cruzi I lineage evidenced by intergenic miniexon gene sequencing. Infect Genet Evol 7 : 587–593.
  30. Murthy VK, Dibbern KM, Campbell DA, 1992. PCR amplification of mini-exon genes differentiates Trypanosoma cruzi from Trypanosoma rangeli. Mol Cell Probes 6 : 237–243.
  31. Machado CA, Ayala FJ, 2002. Sequence variation in the dihydrofolate reductase-thymidylate synthase (DHFR-TS) and trypanothione reductase (TR) genes of Trypanosoma cruzi. Mol Biochem Parasitol 121 : 33–47.
  32. Gaunt M, Miles M, 2000. The ecotopes and evolution of triatomine bugs (triatominae) associated trypanosomes. Mem Inst Oswaldo Cruz 95 : 557–565.
  33. Coronado X, Zulantay I, Rozas M, Apt W, Sánchez G, Rodríguez J, Ortiz S, Solari A, 2006. Dissimilar distribution of Trypanosoma cruzi clones in humans after chemotherapy with allopurinol and itraconazole. J Antimicrob Chemother 58 : 216–219.
  34. Higo H, Yanagi T, Matta V, Agatsuma T, Cruz-Reyes A, Uyema N, Monroy C, Kanbara H, Tada I, 2000. Genetic structure of Trypanosoma cruzi in American continents: special emphasis on sexual reproduction in Central America. Parasitology 121 : 403–408.
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  • Received : 08 Jul 2008
  • Accepted : 20 Oct 2008

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