Volume 80, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


This case-control study examines whether chronic diarrhea at initiation of antiretroviral therapy (ART) affects survival of human immunodefiency virus–infected patients. Cases (288) were treatment-naive, non-pregnant, adults with self report of frequent loose stool for > 3 weeks at the time ART was initiated. One-third of patients had an enteric pathogen identified including spp., spp., , , and . Control patients (400) did not have diarrhea when initiating ART. At six weeks, mortality was 10% in the patients with diarrhea and 5% in the patients without diarrhea ( = 0.009). Chronic diarrhea in patients requesting ART in Haiti is associated with increased early mortality.


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  • Received : 17 Jun 2008
  • Accepted : 15 Feb 2009

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