1921
Volume 81, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Schistosomal myeloradiculopathy (SMR) is the most severe and disabling form of schistosomiasis. The diagnosis is based on clinical, laboratory, and image data. Vestibular-evoked myogenic potential (VEMP) is a neurophysiologic test that assesses the vestibulospinal pathway through acoustic or galvanic stimuli. The aim of this study was to evaluate cervical spinal abnormalities in patients with SMR. Fifty-two subjects were evaluated, of whom 29 had SMR and 30 did not (normal control). Normal VEMP was observed in all volunteers without SMR. Abnormal VEMP was recorded in 34% of the group with SMR. After treatment, abnormal VEMP was found in 80% of those with persistent neurologic abnormalities. VEMP is a functional test, and the alteration may precede image abnormalities. This procedure may be useful for early diagnosis of schistosomal cervical spinal cord involvement.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2009.09-0191
2009-10-01
2017-09-22
Loading full text...

Full text loading...

/deliver/fulltext/14761645/81/4/0810551.html?itemId=/content/journals/10.4269/ajtmh.2009.09-0191&mimeType=html&fmt=ahah

References

  1. Akin FW, Murnane OD, 2001. Vestibular evoked myogenic potentials: preliminary report. J Am Acad Audiol 12: 445–452.
  2. Welgampola SM, Colebatch JG, 2005. Characteristics and clinical applications of vestibular-evoked myogenic potentials. Neurology 64: 1682–1688.
  3. Colebatch JG, Halmagy GM, Skuse NF, 1994. Myogenic potentials generated by a click-evoked vestibulocollic reflex. J Neurol Neurosurg Psychiatry 57: 190–197.
  4. Basta D, Todt I, Ernst A, 2005. Normative data for P1/N1-latencies of vestibular evoked myogenic potentials induced by air- or bone-conducted tone bursts. Clin Neurophysiol 116: 2216–2219.
  5. Perez VG, Gonzales EG, Garcia AP, Piqueral ADR, Morera CP, Perez HG, 2005. Vestibular evoked myogenic potential: a contribution to the vestibular physiology and pathology knowledge. Quantitative patterns in healthy subjects. Acta Otorrinolaringol Esp 56: 349–353.
  6. Felipe L, Carvalho SAS, Cunha LCM, Santos MAR, Peixoto MAL, Gonçalves DU, 2009. Hallazgos de potenciales vestibulares biogénicos evocados en la esclerosis múltiple vestibular evoked myogenic. Rev Neurol 48: 284–286.
  7. Felipe L, Santos MAR, Lambertucci JR, Proietti FA, Carneiro-Proietti AB, Ribas JGR, Gonçalves DU, 2008. Vestibular-evoked myogenic potential (VEMP) to evaluate cervical myelopathy in human T cell lymphotropic virus type I infection. Spine 33: 1180–1184.
  8. Saturcci F, Logi F, 2002. Vestibular-evoked myogenic potentials: a method to assess vestibulo-spinal conduction in multiple sclerosis patients. Brain Res Bull 59: 59–63.
  9. Lambertucci JR, 1993. Schistosoma mansoni: pathological and clinical aspects. Jordan P, Webbe G, eds. Human Schistosomiasis. Wallingford, UK: Cab International, 195–235.
  10. Lambertucci JR, Silva LCS, Amaral RS, 2007. Guidelines for the diagnosis and treatment of schistosomal myeloradiculopathy. Rev Soc Bras Med Trop 40: 574–581.
  11. Centers for Disease Control and Prevention, 1984. Acute schistosomiasis with tranverse myelitis in American students returning from Kenia [editorial note]. Morb Mortal Wkly Rep 33: 446–447.
  12. Silva LCS, Maciel PE, Ribas JGR, Sousa-Pereira SR, Antunes CM, Lambertucci JR, 2004. Treatment of schistosomal myeloradiculopathy with praziquantel and corticosteroids and evaluation by magnetic resonance imaging: a longitudinal study. Clin Infect Dis 39: 1618–1624.
  13. Lambertucci JR, Silva LC, Andrade LM, de Queiroz LC, Carvalho VT, Voieta I, Antunes CM, 2008. Imaging techniques in the evaluation of morbidity in schistosomiasis mansoni. Acta Trop 108: 209–217.
  14. Lambertucci JR, Voieta I, Silveira IS, 2008. Cerebral schistosomiasis mansoni. Rev Soc Bras Med Trop 41: 647–648.
  15. Sousa-Pereira SR, Teixeira AL, Silva LC, Souza AL, Antunes CM, Teixeira MM, Lambertucci JR, 2006. Serum and cerebral spinal fluid levels of chemokines and Th2 cytokines in Schistosoma mansoni myeloradiculopathy. Parasite Immunol 28: 473–478.
  16. Lambertucci JR, Serufo JC, Gerspacher-Lara R, Rayes AAM, Teixeira R, Nobre V, Antunes CMF, 2000. Schistosoma mansoni: assessment of morbidity before and after control. Acta Trop 77: 101–109.
  17. Silva LCS, Kill CM, Lambertucci JR, 2002. Cervical spinal cord schistosomiasis. Rev Soc Bras Med Trop 35: 543–544.
  18. Felipe L, Santos MAR, Gonçalves DU, 2008. Vestibular evoked myogenic potential (VEMP): evaluation of responses in normal subjects. Pró-Fono R Atual 20: 249–254.
  19. Akin FW, Murnane OD, Panus PC, Caruthers SK, Wilkinson AE, Proffitt TM, 2004. The influence of voluntary tonic EMG level on the vestibular-evoked myogenic potential. J Rehabil Res Dev 41: 473–480.
  20. Murofushi T, Shimizu K, Takegoshi H, Cheng PW, 2001. Diagnostic value of prolonged latencies in the vestibular evoked myogenic potential. Arch Otolaryngol Head Neck Surg 127: 1069–1072.
  21. Akkuzu G, Akkuzu B, Ozluoglu LN, 2006. Vestibular evoked myogenic potentials in benign paroxysmal positional vertigo and Meniere’s disease. Eur Arch Otorhinolaryngol 263: 510–517.
  22. Iles JF, Ali AS, Savic G, 2004. Vestibular-evoked muscle responses in patients with spinal cord injury. Brain 127: 1584–1592.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2009.09-0191
Loading
/content/journals/10.4269/ajtmh.2009.09-0191
Loading

Data & Media loading...

  • Received : 14 Apr 2009
  • Accepted : 11 Jul 2009

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error