1921
Volume 81, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

BioUD is an arthropod repellent that contains the active ingredient 2-undecanone originally derived from wild tomato plants. Repellency of BioUD was compared with five commercially available arthropod repellents against the ticks (L.) and Say in two-choice bioassays on treated versus untreated cotton cheesecloth. Overall mean percentage repellency against both species was greatest for and did not differ significantly between BioUD (7.75% 2-undecanone) and products containing 98.1% DEET, 19.6% IR3535, and 30% oil of lemon eucalyptus. Products containing 5% and 15% Picaridin and 0.5% permethrin were also repellent compared with untreated controls but to a lesser degree than BioUD. The four most active repellents at the same concentrations used before were directly compared in head-to-head bioassays on cotton cheesecloth. BioUD provided significantly greater overall mean percentage repellency than IR3535 for and . BioUD was significantly more repellent than oil of lemon eucalyptus for but did not differ significantly in repellency against . No statistically significant difference in overall mean percentage repellency was found between BioUD and DEET for or . In a 7-week time course bioassay, BioUD applied to cotton cheesecloth and held at room temperature provided 5 weeks of > 90% repellency against .

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2009.09-0114
2009-10-01
2017-11-24
Loading full text...

Full text loading...

/deliver/fulltext/14761645/81/4/0810685.html?itemId=/content/journals/10.4269/ajtmh.2009.09-0114&mimeType=html&fmt=ahah

References

  1. Childs JE, Paddock CD, 2003. The ascendancy of Amblyomma americanum as a vector of pathogens affecting humans in the United States. Annu Rev Entomol 48: 307–337.
  2. Sonenshine DE, Lane RS, Nicholson WL, 2002. Ticks (Ixodida). Mullen G, Durden L, eds. Medical and Veterinary Entomology. San Diego: Academic Press, 517–558.
  3. Merten H, Durden LA, 2000. A state-by-state survey of ticks recorded from humans in the United States. J Vector Ecol 25: 102–113.
  4. Frances SP, 2007. Efficacy and safety of products containing DEET. Debboun M, Frances S, Strickman D, eds. Insect Repellents: Principles, Methods, and Uses. Boca Raton, FL: CRC Press, 311–326.
  5. Frances SP, Cooper RD, Sweeney AW, 1998. Laboratory and field evaluation of the repellents, deet, CIC-4 and AI3-37220, against Anopheles farauti (Diptera: Culicidae) in Australia. J Med Entomol 35: 690–693.
  6. Yap HH, Jahangir K, Zairi J, 2000. Field efficacy of four insect repellent products against vector mosquitoes in a tropical environment. J Am Mosq Control Assoc 16: 241–244.
  7. Barnard DR, Xue R-D, 2004. Laboratory evaluation of mosquito repellents against Aedes albopictus, Culex nigripalpus, and Ochlerotatus triseriatus (Diptera: Culicidae). J Med Entomol 41: 726–730.
  8. Evans SR, Korch GW Jr, Lawson MA, 1990. Comparative field evaluation of permethrin and DEET-treated military uniforms for personal protection against ticks (Acari). J Med Entomol 27: 829–834.
  9. Schreck CE, Fish D, McGovern TP, 1995. Activity of repellents applied to skin for protection against Amblyomma americanum and Ixodes scapularis ticks (Acari: Ixodidae). J Am Mosq Control Assoc 11: 136–140.
  10. Solberg VB, Klein TA, McPherson KR, Bradford BA, Burge JR, Wirtz RA, 1995. Field evaluation of DEET and a piperidine repellent (AI3-37220) against Amblyomma americanum. J Med Entomol 32: 870–875.
  11. Osimitz TG, Grothaus RH, 1995. The present safety assessment of deet. J Am Mosq Control Assoc 11: 274–278.
  12. Koren G, Matsui D, Bailey B, 2003. DEET-based insect repellents: safety implications for children and lactating women. Can Med Assoc 169: 209–212.
  13. Sudaken DL, Trevathan WR, 2003. DEET: a review and update of safety and risk in the general population. Clin Toxicol 41: 831–839.
  14. Aquino M, Fyfe M, MacDougall L, Remple V, 2004. West Nile virus in British Columbia. Emerg Infect Dis 10: 1499–1501.
  15. US Environmental Protection Agency, 2007. Active ingredients found in insect repellents. Available at: http://www.epa.gov/pesticides/health/mosquitoes/ai_insectrp.htm. Accessed July 16, 2008.
  16. Breeden GC, Schreck CE, Sorenson AL, 1982. Permethrin as a clothing treatment for personal protection against chigger mites (Acarina: Trombiculidae). Am J Trop Med Hyg 31: 589–592.
  17. Farrar RR, Kennedy GG, 1987. 2-Undecanone, a constituent of the glandular trichomes of Lycopersicon hirsutum f. glabratum: effects on Heliothis zea and Manduca sexta growth and survival. Entomol Exp Appl 43: 17–23.
  18. Witting-Bissinger BE, Stumpf CF, Donohue KV, Apperson CS, Roe RM, 2008. Novel arthropod repellent, BioUD, is an efficacious alternative to deet. J Med Entomol 45: 891–898.
  19. Bissinger BW, Apperson CS, Sonenshine DE, Watson DW, Roe RM, 2009. Efficacy of the new repellent BioUD ® against three species of ixodid ticks. Appl Exp Acarol 48: 239–250.
  20. Smith CN, Gouck HK, 1946. Observations on tick repellents. J Econ Entomol 39: 374–378.
  21. Sonenshine DE, 1993. Biology of Ticks, Vol. 2. New York: Oxford University Press.
  22. SAS Institute, 2000–2004. SAS 9.1.3 Help and Documentation. Cary, NC: SAS Institute.
  23. Draper NR, Smith H, 1981. Applied Regression Analysis. New York: Wiley.
  24. Barnard DR, 1999. Repellency of essential oils to mosquitoes (Diptera: Culicidae). J Med Entomol 36: 625–629.
  25. Jaenson TGT, Pålsson K, Borg-Karlson A-K, 2005. Evaluation of extracts and oils of tick-repellent plants from Sweden. Med Vet Entomol 19: 345–352.
  26. Jaenson TGT, Garboui S, Pålsson K, 2006. Repellency of oils of lemon eucalyptus, geranium and lavender and the mosquito repellent MyggA Natural to Ixodes ricinus (Acari: Ixodidae) in the laboratory and field. J Med Entomol 43: 731–736.
  27. Moore SJ, Lenglet A, Hill N, 2007. Plant-based insect repellents. Debboun M, Frances S, Strickman D, eds. Insect Repellents: Principles, Methods, and Uses. Boca Raton, FL: CRC Press, 275–303.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2009.09-0114
Loading
/content/journals/10.4269/ajtmh.2009.09-0114
Loading

Data & Media loading...

  • Received : 02 Mar 2009
  • Accepted : 12 Jul 2009

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error