1921
Volume 79, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

A prospective series of 65 patients with surgically confirmed lung cystic hydatid disease was evaluated in terms of their radiologic characteristics, serologic response, and presence of cysts in other organs. Cysts were mostly single and located in lower lung lobes. Liver compromise was found in 34% of the patients. Despite a systematic search, no patient showed brain cysts in this series. Twelve patients had previous hydatid disease: six in the liver and eight in the lung (two had involvement of both organs in the past). Serology using bovine cyst fluid in an immunoblot assay was 85% sensitive. Serologic response was not associated with number or cyst or compromise of other organs but was clearly associated to the presence of at least one complicated cyst. Cyst status in terms of complications should be described to allow appropriate assessment of serologic evaluations.

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2008-07-01
2017-11-18
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References

  1. Eckert J, Deplazes P, 2004. Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clin Microbiol Rev 17 : 107–135.
  2. McManus DP, Zhang W, Li J, Bartley BP, 2003. Echinococcosis. Lancet 362 : 1295–1304.
  3. Morar R, Feldman C, 2003. Pulmonary echinococcosis. Eur Respir J 21 : 1069–1077.
  4. Rebhandl W, Turnbull J, Felberbauer FX, Tasci E, Puig S, Auer H, Paya K, Kluth D, Tasci O, Horcher E, 1999. Pulmonary echinococcosis (hydatidosis) in children: results of surgical treatment. Pediatr Pulmonol 27 : 336–340.
  5. Burgos R, Varela A, Castedo E, Roda J, Montero CG, Serrano S, Tellez G, Ugarte J, 1999. Pulmonary hydatidosis: surgical treatment and follow-up of 240 cases. Eur J Cardiothorac Surg 16 : 628–634.
  6. Dakak M, Genc O, Gurkok S, Gozubuyuk A, Balkanli K, 2002. Surgical treatment for pulmonary hydatidosis (a review of 422 cases). J R Coll Surg Edinb 47 : 689–692.
  7. Keramidas D, Mavridis G, Soutis M, Passalidis A, 2004. Medical treatment of pulmonary hydatidosis: complications and surgical management. Pediatr Surg Int 19 : 774–776.
  8. Shalabi RI, Ayek AK, Amin M, 2002. 15 Years in surgical management of pulmonary hydatidosis. Ann Thorac Cardiovasc Surg 8 : 131–134.
  9. Sotomayor A, 2000. Cirugía. Tomo X. Cirugía de Tórax y Cardiovascular. Lima, Peru: Fondo Edit. UNMSM.
  10. Aribas OK, Kanat F, Turk E, Kalayci MU, 2002. Comparison between pulmonary and hepatopulmonary hydatidosis. Eur J Cardiothorac Surg 21 : 489–496.
  11. Altinors N, Bavbek M, Caner HH, Erdogan B, 2000. Central nervous system hydatidosis in Turkey: a cooperative study and literature survey analysis of 458 cases. J Neurosurg 93 : 1–8.
  12. Khaldi M, Mohamed S, Kallel J, Khouja N, 2000. Brain hydatidosis: report on 117 cases. Childs Nerv Syst 16 : 765–769.
  13. Turgut M, 2002. Hydatidosis of central nervous system and its coverings in the pediatric and adolescent age groups in Turkey during the last century: a critical review of 137 cases. Childs Nerv Syst 18 : 670–683.
  14. Gottstein B, Reichen J, 2002. Hydatid lung disease (echinococcosis/hydatidosis). Clin Chest Med 23 : 397–408.
  15. Kumar A, Lal BK, Chattopadhyay TK, 1992. Radiologic diagnosis of hydatid disease of the liver. Trop Gastroenterol 13 : 52–55.
  16. Pedrosa I, Saíz A, Arrazola J, Ferreirós J, Pedrosa CS, 2000. Hydatid disease: radiologic and pathologic features and complications. Radiographics 20 : 795–817.
  17. Force L, Torres JM, Carrillo A, Buscà J, 1992. Evaluation of eight serological tests in the diagnosis of human echinococcosis and follow-up. Clin Infect Dis 15 : 473–480.
  18. Gadea I, Ayala G, Diago MT, Cuñat A, Garcia de Lomas J, 2000. Immunological diagnosis of human hydatid cyst relapse: utility of the enzyme-linked immunoelectrotransfer blot and discriminant analysis. Clin Diagn Lab Immunol 7 : 549–552.
  19. Lawn SD, Bligh J, Craig PS, Chiodini PL, 2004. Human cystic echinococcosis: evaluation of post-treatment serologic follow-up by IgG subclass antibody detection. Am J Trop Med Hyg 70 : 329–335.
  20. Ravinder PT, Parija SC, Rao KS, 1997. Evaluation of human hydatid disease before and after surgery and chemotherapy by demonstration of hydatid antigens and antibodies in serum. J Med Microbiol 46 : 859–864.
  21. Zhang W, Li J, McManus DP, 2003. Concepts in immunology and diagnosis of hydatid disease. Clin Microbiol Rev 16 : 18–36.
  22. Ortona E, Rigano R, Buttari B, Delunardo F, Ioppolo S, Margutti P, Profumo E, Vaccari S, Siracusano A, 2003. An update on immunodiagnosis of cystic echinococcosis. Acta Trop 85 : 165–171.
  23. Verastegui M, Moro P, Guevara A, Rodriguez T, Miranda E, Gilman RH, 1992. Enzyme-linked immunoelectrotransfer blot test for diagnosis of human hydatid disease. J Clin Microbiol 30 : 1557–1561.
  24. Moro PL, Gonzales AE, Gilman RH, 2000. Cystic hydatid disease. Strickland T, ed. Hunter’s Tropical Medicine and Emerging Infectious Diseases. Philadelphia: Saunders, 866–871.
  25. MacPherson CN, Romig T, Zeyhle E, Rees PH, Were JB, 1987. Portable ultrasound scanner versus serology in screening for hydatid cysts in a nomadic population. Lancet 2 : 259–261.
  26. Shambesh MA, Craig PS, Macpherson CN, Rogan MT, Gusbi AM, Echtuish EF, 1999. An extensive ultrasound and serologic study to investigate the prevalence of human cystic echinococcosis in northern Libya. Am J Trop Med Hyg 60 : 462–468.
  27. Zarzosa MP, Orduna A, Gutierrez P, Alonso P, Cuervo M, Prado A, Bratos MA, Garcia-Yuste M, Ramos G, Rodriguez-Torres A, 1999. Evaluation of six serological tests in diagnosis and postoperative control of pulmonary hydatid disease patients. Diagn Microbiol Infect Dis 35 : 255–262.
  28. Dervenis C, Delis S, Avgerinos C, Madariaga J, Milicevic M, 2005. Changing concepts in the management of liver hydatid disease. J Gastrointest Surg 9 : 869–877.
  29. Simsek S, Koroglu E, 2004. Evaluation of enzyme-linked immunosorbent assay (ELISA) and enzyme-linked immunoelectrotransfer blot (EITB) for immunodiagnosis of hydatid diseases in sheep. Acta Trop 92 : 17–24.
  30. Moro PL, Garcia HH, Gonzales AE, Bonilla JJ, Verastegui M, Gilman RH, 2005. Screening for cystic echinococcosis in an endemic region of Peru using portable ultrasonography and the enzyme-linked immunoelectrotransfer blot (EITB) assay. Parasitol Res 96 : 242–246.
  31. Darwish B, 2006. Clinical and radiological manifestations of 206 patients with pulmonary hydatidosis over a ten-year period. Prim Care Respir J 15 : 246–251.
  32. Dincer SI, Demir A, Sayar A, Gunluoglu MZ, Kara HV, Gurses A, 2006. Surgical treatment of pulmonary hydatid disease: a comparison of children and adults. J Pediatr Surg 41 : 1230–1236.
  33. Dueger EL, Verastegui M, Gilman RH, 2003. Evaluation of the enzyme-linked immunoelectrotransfer blot (EITB) for ovine hydatidosis relative to age and cyst characteristics in naturally infected sheep. Vet Parasitol 114 : 285–293.
  34. Alvarez F, Blazquez MG, Oliver B, Manrique M, 1982. Calcified cerebral hydatid cyst. Surg Neurol 17 : 163–164.
  35. Micheli F, Lehkuniec E, Giannaula R, Caputi E, Paradiso G, 1987. Calcified cerebral hydatid cyst. Eur Neurol 27 : 1–4.
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  • Received : 27 Aug 2007
  • Accepted : 08 Feb 2008

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