Volume 79, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Among ill returned travelers to -endemic areas reported to the GeoSentinel Surveillance Network over a decade 410 schistosomiasis diagnoses were identified: 102 , 88 , 7 , and 213 unknown human species. A total of 83% were acquired in Africa. Unlike previous large case series, individuals born in endemic areas were excluded. Controlling for age and sex, those traveling for missionary or volunteer work, or as expatriates were more likely to be diagnosed with schistosomiasis. Sixty-three percent of those with schistosomiasis presented within six months of travel. Those seen early more often presented with fever and respiratory symptoms compared with those who presented later. One-third of patients with schistosomiasis were asymptomatic at diagnosis. Half of those examined for schistosomiasis were diagnosed with infection. Screening for schistosomiasis should be encouraged for all potentially exposed travelers and especially for missionaries, volunteers, and expatriates.


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  1. Steinmann P, Keiser J, Bos R, Tanner M, Utzinger J, 2006. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infect Dis 6 : 411–425.
  2. Chitsulo L, Engels D, Montresor A, Savioli L, 2000. The global burden of schistosomiasis and its control. Acta Trop 77 : 41–51.
  3. Engels D, Chitsulo L, Montresor A, Savioli L, 2002. The global epidemiological situation of schistosomiasis and new approaches to control and research. Acta Trop 82 : 139–146.
  4. Strickland GT, Ramirez BL, 2000. Schistosomiasis. Strickland GT, ed. Hunter’s Tropical Medicine. Eighth edition. Philadelphia, PA: W.B. Saunders Company, 804–832.
  5. Zuidema PJ, 1981. The Katayama syndrome; an outbreak in Dutch tourists to the Omo National Park, Ethiopia. Trop Geogr Med 33 : 30–35.
  6. Centers for Disease Control and Prevention, 1982. Cercarial dermatitis among bathers in California; Katayama syndrome among travelers to Ethiopia. Morbid Mortal Wkly Rep 31 : 435–438.
  7. Centers for Disease Control and Prevention, 1984. Acute schistosomiasis with transverse myelitis in American students returning from Kenya. Morbid Mortal Wkly Rep 33 : 445–447.
  8. Centers for Disease Control and Prevention, 1990. Acute schistosomiasis in U.S. travelers returning from Africa. Morbid Mortal Wkly Rep 39 : 141–142, 147–148.
  9. Colebunders R, Verstraeten T, Van Gompel A, Van den Ende J, De Roo A, Polderman A, Visser L, 1995. Acute schistosomiasis in travelers returning from Mali. J Travel Med 2 : 235–238.
  10. Schwartz E, Kozarsky P, Wilson M, Cetron M, 2005. Schistosome infection among river rafters on Omo River, Ethiopia. J Travel Med 12 : 3–8.
  11. Bierman W, Wetsteyn J, van Gool T, 2005. Presentation and diagnosis of imported schistosomiasis: relevance of eosinophilia, microscopy for ova, and serology. J Trav Med 12 : 9–13.
  12. Cetron MS, Chitsulo L, Sullivan JJ, Pilcher J, Wilson M, Noh J, Tsang V, Hightower A, Addiss D, 1996. Schistosomiasis in Lake Malawi. Lancet 348 : 1274–1278.
  13. Jelinek T, Nothdurft HD, Loscher T, 1996. Schistosomiasis in travelers and expatriates. J Travel Med 3 : 160–164.
  14. Day J, Grant AD, Doherty JF, Chiodini PL, Wright SG, 1996. Schistosomiasis in travelers returning from sub-Saharan Africa. BMJ 313 : 268–269.
  15. Doherty JF, Moody AH, Wright SG, 1996. Katayama fever: an acute manifestation of schistosomiasis. BMJ 313 : 1071–1072.
  16. Witty CJM, Mabey DC, Armstrong M, Wright SG, Chiodini PL, 2000. Presentation and outcome of 1107 cases of schistosomiasis from Africa diagnosed in a non-endemic country. Trans R Soc Trop Med Hyg 94 : 531–534.
  17. Meltzer E, Artom G, Marva E, Assous MV, Rahav G, Schwartz E, 2006. Schistosomiasis among travelers: new aspects of an old disease. Emerg Infect Dis 12 : 1696–1700.
  18. Bottieau E, Clerinx J, de Vega MR, Van den Enden E, Colebunders R, Van Esbroeck M, Vervoort T, Van Gompel A, Van den Ende J, 2006. Imported Katayama fever: clinical and biological features at presentation and during treatment. J Infect 52 : 339–345.
  19. Thors C, Holmblad P, Maleki M, Carlson J, Linder E, 2006. Schistosomiasis in Swedish travelers to sub-Saharan Africa: can we rely on serology? Scand J Infect Dis 38 : 794–799.
  20. Grobusch MP, Muhlberger N, Jelinek T, Bisoffi Z, Corachan M, Harms G, Matteelli A, Fry G, Hatz C, Gjorup I, Schmid ML, Knobloch J, Puente S, Bronner U, Kapaun A, Clerinx J, Nielsen LN, Fleischer K, Beran J, 2003. Imported schistosomiasis in Europe: sentinel surveillance data from TropNet Europe. J Travel Med 10 : 164–167.
  21. Bottieau E, Clerinx J, Van den Enden E, Van Esbroeck M, Colebunders R, Van Gompel A, Van den Ende J, 2006. Fever after a stay in the tropics, diagnostic predictors of the leading tropical conditions. Medicine 86 : 18–25.
  22. Freedman DO, Kozarsky PE, Weld LH, Cetron MS, 1999. Geo-Sentinel: the global emerging infections sentinel network of the International Society of Travel Medicine. J Travel Med 6 : 94–98.
  23. Freedman DO, Weld L, Kozarsky P, Fisk T, Robins R, von Sonnenburg F, Keystone J, Pandey P, Cetron M, 2006. Spectrum of disease and relation to place of exposure among ill returned travelers. N Engl J Med 354 : 119–130.
  24. Montgomery S, 2007. Schistosomiasis. In Centers for Disease Control and Prevention. Health Information for International Travel 2008. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service; 2007, 297–301.
  25. Tsang V, Wilkins PP, 1997. Immunodiagnosis of schistosomiasis. Immunol Invest 26 : 175–188.
  26. United Nations Statistics Division, Composition of macro geographical (continental) regions, geographical sub-regions, and selected economic and other groupings. Available at: http://unstats.un.org/unsd/methods/m49/m49regin.htm. Accessed June 9, 2008.
  27. Witty C, Carroll B, Armstrong M, Dow C, Snashall D, Marshall T, Chiodini P, 2000. Utility of history, examination and laboratory test in screening those returning to Europe from the tropics for parasitic infection. Trop Med Int Health 5 : 818–823.
  28. Outwater A, Mpangala E, 2005. Schistosomiasis in US Peace Corps volunteers in Tanzania. J Travel Med 12 : 265–269.
  29. Rocha M, Rocha RL, Pedroso E, Greco D, Ferreira C, Lambertucci J, Katz N, Rocha RS, Rezende D, Neves J, 1995. Pulmonary manifestations in the initial phase of Schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo 37 : 311–318.
  30. Cooke GS, Lalvani A, Gleeson FV, Conlon CP, 1999. Acute pulmonary schistosomiasis in travelers returning from Lake Malawi, sub-Saharan Africa. Clin Infect Dis 29 : 836–839.
  31. Schwartz E, Rozenman J, Perelman M, 2000. Pulmonary manifestations of early schistosome infection among non-immune travelers. Am J Med 109 : 718–722.

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  • Received : 14 Nov 2007
  • Accepted : 17 Jul 2008

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