1921
Volume 79, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Cutaneous leishmaniasis (CL) is a widespread disease in Suriname caused by . It is argued that other species are also responsible for CL and that the incidence is increasing. This study aimed to identify the species causing the disease and to estimate the annual detection rate of CL in Suriname in 2006. In Paramaribo, 152 patients were registered, of whom 33 were tested in two polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) methods. Twenty-seven patients were infected with (complex), one with and one with In the hinterland, 162 CL suspected patients were registered by questionnaires; of these, 24 of 27 tested positive by PCR-RFLP (88.9%; 95% CI, 77.1–100%). With extrapolation of collected data, a detection rate was calculated of 5.32 to 6.13 CL patients per 1,000 inhabitants for the hinterland and 0.64 to 0.74 patients per 1,000 inhabitants for the whole country.

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2008-08-01
2017-11-23
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References

  1. WHO, 2004. The World Health Report. Geneva: World Health Organization.
  2. Flu PC, 1911. Die aetiologie der in Surinam vorkommenden sogenannten “Boschyaws”, einer der Aleppobeule analogen Erkrankung. Centralbl Bakt Parasit Kde Orig 60 : 624–637.
  3. Burgos A, Hudson J, 1994. Annotated list of the phlebotominae (diptera) of Suriname. Mem Inst Oswaldo Cruz 89 : 171–178.
  4. Wijers D, Linger R, 1966. Man-biting sandflies in Surinam (Dutch Guiana): Phlebotomus anduzei as a possible vector of Leishmania braziliensis. Ann Trop Med Parasitol 60 : 501–508.
  5. Hudson J, Young DG, 1985. New records of phlebotomines, leishmaniasis and mosquitoes from Suriname. Trans R Soc Trop Med Hyg 79 : 418.
  6. Rotureau B, 2006. Ecology of the Leishmania species in the guianan ecoregion complex. Am J Trop Med Hyg 74 : 81–96.
  7. Lai A, Fat EJ, Vrede MA, Soetosenojo RM, Lai A, Fat RF, 2002. Pentamidine, the drug of choice for the treatment of cutaneous leishmaniasis in Surinam. Int J Dermatol 41 : 796–800.
  8. Winckel W, Aalstein M, 1953. Contribution to the geographical pathology of Suriname: first case of kalaazar in Surinam. Doc Med Geogr Trop 5 : 339–342.
  9. Herwaldt BL, 1999. Leishmaniasis. Lancet 354 : 1191–1199.
  10. Blum J, Desjeux P, Schwartz E, Beck B, Hatz C, 2004. Treatment of cutaneous leishmaniasis among travelers. J Antimicrob Chemother 53 : 158–166.
  11. Rioux JA, Lanotte G, Serres E, Pratlong F, Bastien P, Perieres J, 1990. Taxonomy of Leishmania. Use of isoenzymes. Suggestions for a new classification. Ann Parasitol Hum Comp 65 : 111–125.
  12. Garcia L, Kindt A, Bermudez H, Llanos-Cuentas A, De Doncker S, Arevalo J, Tintaya K, Dujardin J, 2004. Culture-independent species typing of neotropical Leishmania for clinical validation of a PCR-based assay targeting heat shock protein 70 genes. J Clin Microbiol 42 : 2294–2297.
  13. Marfurt J, Nasereddin A, Niederwieser I, Jaffe C, Beck H, Felger I, 2003. Identification and differentiation of Leishmania species in clinical samples by PCR amplification of the miniexon sequence and subsequent restriction fragment length polymorphism analysis. J Clin Microbiol 41 : 3147–3153.
  14. Schönian G, Nasereddin A, Dinse N, Schweynoch C, Schallig HDFH, Presber W, Jaffe CL, 2003. PCR diagnosis and characterization of Leishmania in local and imported clinical samples. Diagn Microbiol Infect Dis 47 : 349–358.
  15. Desjeux P, 2004. Leishmaniasis: current situation and new perspectives. Comp Immunol Microbiol Infect Dis 27 : 305–318.
  16. van der Meide WF, Schoone GJ, Faber WR, Zeegelaar JE, de Vries HJ, Ozbel Y, Lai A, Fat RF, Coelho LI, Kassi M, Schallig HD, 2005. Quantitative nucleic acid sequence-based assay as a new molecular tool for the detection and quantification of Leishmania parasites in skin biopsies. J Clin Microbiol 43 : 5560–5566.
  17. Rotureau B, Ravel C, Nacher M, Couppié P, Curtet I, Dedet J-P, Carme B, 2006. Molecular epidemiology of Leishmania (Viannia) guyanensis in French Guiana. J Clin Microbiol 44 : 468–473.
  18. Convit J, Ulrich M, Fernandez CT, Tapia FJ, Caceres-Dittmar G, Castes M, Rondon AJ, 1993. The clinical and immunological spectrum of American cutaneous leishmaniasis. Trans R Soc Trop Med Hyg 87 : 444–448.
  19. Esterre P, Chippaux JP, Lefait JF, Dedet JP, 1986. Evaluation of a cutaneous leishmaniasis control program in a forest village of French Guyana. Bull World Health Organ 64 : 559–565.
  20. Rotureau B, Joubert M, Clyti E, Djossou F, Carme B, 2006. Leishmaniasis among gold miners, French Guiana. Emerg Infect Dis 12 : 1169–1170.
  21. Copeland HW, Arana BA, Navin TR, 1990. Comparison of active and passive case detection of cutaneous leishmaniasis in Guatemala. Am J Trop Med Hyg 43 : 257–259.
  22. Dedet J, Pradinaud R, Gay F, 1989. Epidemiological aspects of human cutaneous leishmaniasis in French Guiana. Trans R Soc Trop Med Hyg 83 : 616–620.
  23. Chaves LF, Pascual M, 2006. Climate cycles and forecasts of cutaneous leishmaniasis, a nonstationary vector-borne disease. PLoS Medicine 3 : e295.
  24. Sutherst RW, 2004. Global change and human vulnerability to vector-borne diseases. Clin Microbiol Rev 17 : 136–173.
  25. Cardenas R, Sandoval CM, Rodriguez-Morales AJ, Franco-Paredes C, 2006. Impact of climate variability in the occurrence of leishmaniasis in northeastern Colombia. Am J Trop Med Hyg 75 : 273–277.
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  • Received : 16 Sep 2007
  • Accepted : 05 May 2008

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