Volume 78, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Resistance of to organophosphate and carbamate insecticides was first reported in Côte d’Ivoire, West Africa. Subsequent studies revealed that it resulted from a single point mutation in the oxyanion hole of the acetycholinesterase enzyme ( mutation). We investigated the distribution and prevalence of the mutation in s.l. populations from seven locations in south-western Burkina Faso. The mutation was found in both M and S molecular forms of s.s but it was absent in . Its frequency ranged from 0.25 to 0.5 in S form and 0.04 to 0.13 in M form, though they were sympatric. The lack of homozygous resistance indicated a strong genetic cost associated with the mutation. These data suggest that organophosphate and carbamate resistance conferred by target site insensitivity is spreading in populations of s.s. from West Africa.


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  • Received : 26 May 2007
  • Accepted : 31 Oct 2007

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