1921
Volume 78, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Both hyperreactive malarial splenomegaly (HMS) and HIV infection are highly prevalent in sub-Saharan Africa, but the inter-relationships between the two conditions are not clearly defined. Diagnosis of HMS is particularly difficult in HIV-infected patients, and detection of circulating malaria parasites by polymerase chain reaction (PCR) may represent a useful diagnostic tool.

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/content/journals/10.4269/ajtmh.2008.78.239
2008-02-01
2017-11-21
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References

  1. Van den Ende J, 2000. Hyperreactive malaria in expatriates returning from sub-Saharan Africa. Trop Med Int Health 5 : 607–611.
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  3. Korenromp EL, Williams BG, de Vlas SJ, 2005. Malaria attributable to the HIV-1 epidemic, sub-Saharan Africa. Emerg Infect Dis 11 : 1410–1419.
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  7. Duarte MI, Boulos M, 1997. Hyperreactive malarious splenomegaly: immunohistochemical demonstration of Plasmodium falciparum antigen in liver cells. Trans R Soc Trop Med Hyg 91 : 429–430.
  8. Vinetz JM, Li J, Mc Cutchan TF, Kaslow DC, 1998. Plasmodium malariae infection in an asymptomatic 74-year-old Greek woman with splenomegaly. N Engl J Med 338 : 367–371.
  9. Bottius E, Guanzirolli A, Trape J-F, Rogier C, Konate L, Druilhe P, 1996. Malaria: even more chronic in nature than previously thought; evidence for subpatent parasitaemia detectable by the polymerase chain reaction. Trans R Soc Trop Med Hyg 90 : 15–19.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2008.78.239
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  • Received : 07 Aug 2006
  • Accepted : 03 Apr 2007

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