Volume 78, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Both hyperreactive malarial splenomegaly (HMS) and HIV infection are highly prevalent in sub-Saharan Africa, but the inter-relationships between the two conditions are not clearly defined. Diagnosis of HMS is particularly difficult in HIV-infected patients, and detection of circulating malaria parasites by polymerase chain reaction (PCR) may represent a useful diagnostic tool.


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  • Received : 07 Aug 2006
  • Accepted : 03 Apr 2007

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