Volume 78, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


The tapeworm (Cestoda: Diphyllobothriidea), originally described from Japan, is reported from a man in North America for the first time. Species identification was based on sequences of ribosomal (partial 18S rRNA) and mitochondrial (partial Cytochrome c Oxidase subunit I) genes of proglottids expelled from a Czech tourist who ate raw Pacific sockeye salmon () from British Columbia, Canada.


Article metrics loading...

Loading full text...

Full text loading...



  1. Muller R, 2002. Worms and Human Disease. Second Edition. Wallingford, PA: CABI Publishing.
  2. Chai J-Y, Murrell KD, Lymbery AJ, 2005. Fish-borne parasitic zoonoses: status and issues. Int J Parasitol 35 : 1233–1254.
  3. Rausch RL, Hilliard DK, 1970. Studies on the helminth fauna of Alaska. XLIX. The occurrence of Diphyllobothrium latum (Linnaeus, 1758) (Cestoda: Diphyllobothriidae) in Alaska, with notes on other species. Can J Zool 48 : 1201–1219.
  4. Andersen K, Ching HL, Vik R, 1987. A review of freshwater species of Diphyllobothrium with redescriptions and the distribution of D. dendriticum (Nitzsch, 1824) and D. ditremum (Creplin, 1825) from North America. Can J Zool 65 : 2216–2228.
  5. Margolis L, Rausch RL, Robertson E, 1973. Diphyllobothrium ursi from man in British Columbia—first report of this tapeworm in Canada. Can J Publ Hlth 64 : 588–589.
  6. Yamane Y, Kamo H, Bylund G, Wikgren Bo-J, 1986. Diphyllobothrium nihonkaiense sp. nov. (Cestoda: Diphyllobothriidae)—revised identification of Japanese broad tapeworm. Shimane J Med Sci 10 : 29–48.
  7. Jeon H, Kim K-H, Park J-K, Eom KS, Chai JY, 2003. Dominance of Diphyllobothrium nihonkaiense (family Diphyllobothriidae) inferred from the nucleotide sequences of ribosomal ITS1 and mtCox1 in Korea. The 45th Annual Meeting of the Korean Society for Parasitology.
  8. Yoshida M, Hasegawa H, Takaoka H, Miyata A, 1999. A case of Diphyllobothrium nihonkaiense infection successfully treated by oral administration of Gastrografin. Parasitol Int 48 : 151–155.
  9. Ando K, Ishikura K, Nakakugi T, Shimono Y, Tamai T, Sugawa M, Limviroj W, Chinzei Y, 2001. Five cases of Diphyllobothrium nihonkaiense infection with discovery of plerocercoids from an infective source, Oncorhynchus masou ishikawae. J Parasitol 87 : 96–100.
  10. Hoffman GL, 1999. Parasites of North American Freshwater Fishes. Second Edition. Ithaca & London: Cornell University Press.
  11. Froese R, Pauly D (eds.), 2007. FishBase. World Wide Web electronic publication, accessed August 2007. http://www.fishbase.org.
  12. Mariaux J, 1998. A molecular phylogeny of the Cestoda. J Parasitol 84 : 114–124.
  13. Bowles J, Blair D, McManus DP, 1992. Genetic variants within the genus Echinococcus identified by mitochondrial DNA sequencing. Mol Biochem Parasitol 54 : 165–173.
  14. Kumar S, Tamura K, Nei M, 2004. MEGA3: integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform 5 : 150–163.
  15. Wicht B, de Marval F, Peduzzi R, 2007. Diphyllobothrium nihonkaiense (Yamane et al., 1986) in Switzerland: first molecular evidence and case reports. Parasitol Int 56 : 195–199.
  16. Miyadera H, Kokaze A, Kuramochi T, Kita K, Machinami R, Noyae O, Alarcon de Noyae B, Okamoto M, Kojima S, 2001. Phylogenetic identification of Sparganum proliferum as a pseudophyllidean cestode by the sequence analyses on mitochondrial COI and nuclear sdhB genes. Parasitol Int 50 : 93–104.
  17. Yera H, Estran C, Delaunay P, Gari-Toussaint M, Dupouy-Camet J, Marty P, 2006. Putative Diphyllobothrium nihonkaiense acquired from a Pacific salmon (Oncorhynchus keta) eaten in France; genomic identification and case report. Parasitol Int 55 : 45–49.
  18. Škeříková A, Brabec J, Kuchta R, Jiménez JA, García HH, Scholz T, 2006. Is the human-infecting Diphyllobothrium pacificum a valid species or just a South American population of the Holarctic fish broad tapeworm, D. latum? Am J Trop Med Hyg 75 : 307–310.
  19. Baer JG, 1969. Diphyllobothrium pacificum, a tapeworm from sea lions endemic in man along the coastal area of Peru. J Fish Res Board Can 26 : 717–723.
  20. Tsuboi T, Torii M, Hirai K, 1993. Light and scanning electron microscopy of Diphyllobothrium pacificum expelled from a man. Jap J Parasitol 42 : 422–428.
  21. Andersen K, Halvorsen O, 1978. Egg size and form as taxonomic criteria in Diphyllobothrium. Parasitology 76 : 229–240.
  22. Delyamure SL, Skryabin AS, Serdiukov AM, 1985. Diphyllobothriata—Flatworms of Man, Mammals and Birds. Principles of Cestodology. Volume IX. Moscow, Russia: Nauka. [In Russian.]
  23. Kamo H, Maejima J, Yazaki S, 1982. Occurrence of human infection with Diphyllobothrium pacificum (Nybelin, 1931) Margolis, 1956 in Japan. Jap J Parasitol 31 : 165–170.
  24. Dupouy-Camet J, Peduzzi R, 2004. Current situation of human diphyllobothriasis in Europe. Eurosurveillance 9 : 31–34.
  25. Torres P, Cuevas C, Tang M, Barra M, Franjola R, Navarrete N, Montefusco A, Otth L, Wilson G, Puga S, Figueroa L, Cerda O, 2004. Introduced and native fishes as infection foci of Diphyllobothrium spp. in humans and dogs from two localities at Lake Panguipulli in Southern Chile. Comp Parasitol 71 : 111–117.
  26. Santos FLN, de Faro LB, 2005. The first confirmed case of Diphyllobothrium latum in Brazil. Mem Inst Oswaldo Cruz 100 : 585–586.
  27. Wicht B, de Marval F, Gottstein B, Peduzzi R, 2007. Imported diphyllobothriasis in Switzerland: molecular evidence of Diphyllobothrium dendriticum (Nitsch, 1824). Parasitol Res 102 : 201–204.
  28. Kim K-H, Jeon H-K, Kang S, Sultana T, Eom KS, Park JK, 2007. Characterization of the complete mitochondrial genome of Diphyllobothrium nihonkaiense (Diphyllobothriidae: Cestoda), and development of molecular markers for differentiating fish tapeworms. Mol Cells 23 : 379–390.

Data & Media loading...

  • Received : 04 Sep 2007
  • Accepted : 16 Nov 2007

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error