1921
Volume 78, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

In this study, 336 bats of eight species were collected during 2004–2007 in six provinces of Southern China. Antibodies against Japanese encephalitis virus (JEV) were detected by ELISA in 43 of 336 (12.8%) serum samples. Among those ELISA-positive samples, 11 serum samples had neutralizing antibodies against JEV. No JEV was detected in brain and liver samples using specific real-time reverse transcriptase-polymerase chain reaction. This is the first report of JEV neutralizing antibodies in bats in China, which reinforces that bats can be involved in the life cycle of this virus.

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2008-06-01
2019-07-16
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References

  1. Sumiyoshi H, Mori C, Fuke I, Morita K, Kuhara S, Kondou J, Kikuchi Y, Nagamatu H, Igarashi A, 1987. Complete nucleotide sequence of the Japanese encephalitis virus genome RNA. Virology 161 : 497–510. [Google Scholar]
  2. Mackenzie JS, Barrett AD, Deubel V, 2002. The Japanese encephalitis serological group of flaviviruses: a brief introduction to the group. Clin Microbiol Rev 267 : 1–10. [Google Scholar]
  3. Solomon T, Vaughn DW, 2002. Pathogenesis and clinical features of Japanese encephalitis and West Nile virus infections. Curr Top Microbiol Immunol 267 : 171–194. [Google Scholar]
  4. Mackenzie JS, Gubler DJ, Petersen LR, 2004. Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses. Nat Med 10 : S98–S109. [Google Scholar]
  5. Miura T, Toyokawa K, Allen R, Sulkin SE, 1970. Studies of arthropod-borne virus infections in Chiroptera. VII. Serologic evidence of natural Japanese B encephalitis virus infection in bats. Am J Trop Med Hyg 19 : 88–93. [Google Scholar]
  6. Banerjee K, Bhat HR, Geevarghese G, Jacob PG, Malunjkar AS, 1988. Antibodies against Japanese encephalitis virus in insectivorous bats from Karnataka. Indian J Med Res 87 : 527–530. [Google Scholar]
  7. Calisher CH, Childs JE, Field HE, Holmes KV, Schountz T, 2006. Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev 19 : 531–545. [Google Scholar]
  8. Sulkin SE, Allen R, Miura T, Toyokawa K, 1970. Studies of arthropod-borne virus infections in Chiroptera. VI. Isolation of Japanese B encephalitis virus from naturally infected bats. Am J Trop Med Hyg 19 : 77–87. [Google Scholar]
  9. Paul SD, Rajagopalan PK, Screenivasan MA, 1970. Isolation of the West Nile virus from the frugivorous bat, Rousettus leschenaulti. Indian J Med Res 58 : 1169–1171. [Google Scholar]
  10. Bunde JM, Heske EJ, Mateus-Pinilla NE, Hofmann JE, Novak RJ, 2006. A survey for West Nile virus in bats from Illinois. J Wildl Dis 42 : 455–458. [Google Scholar]
  11. Marfin AA, Petersen LR, Eidson M, Miller J, Hadler J, Farello C, Werner B, Campbell GL, Layton M, Smith P, Bersnitz E, Cartter M, Scaletta J, Obira G, Bunning M, Craven RC, Roehrig JT, Julian KG, Hinten SR, Gubler DJ, ArboNET Cooperative Surveillance Group, 2001. Widespread West Nile virus activity, eastern United States, 2000. Emerg Infect Dis 7 : 730–735. [Google Scholar]
  12. Pilipski JD, Pilipski LM, Risley LS, 2004. West Nile virus antibodies in bats from New Jersey and New York. J Wildl Dis 40 : 335–337. [Google Scholar]
  13. Rossi CA, Ksiazek TG, 1999. Enzyme-linked immunosorbent assay (ELISA). Lee HW, Calisher C, Schmaljohn C, eds. Manual of Hemorrhagic Fever with Renal Syndrome and Hantavirus Pulmonary Syndrome. Seoul: Asan Institute for Life Sciences, 87–91.
  14. Schoenthaler SL, Kapil S, 1999. Development and application of a bovine coronavirus antigen detection enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol 6 : 130–132. [Google Scholar]
  15. Shirato K, Miyoshi H, Kariwa H, Takashima I, 2005. Detection of West Nile virus and Japanese encephalitis virus using real-time PCR with a probe common to both viruses. J Virol Methods 126 : 119–125. [Google Scholar]
  16. Solomon T, Ni H, Beasley DWC, Ekkelenkamp M, Cardosa MJ, Barrett ADT, 2003. Origin and evolution of Japanese encephalitis virus in Southeast Asia. J Virol 77 : 3091–3098. [Google Scholar]
  17. Wang HY, Takasaki T, Fu SH, Sun XH, Zhang HL, Wang ZX, Hao ZY, Zhang JK, Tang Q, Kotaki A, Tajima S, Liang XF, Yang WZ, Kurane I, Liang GD, 2007. Molecular epidemiological analysis of Japanese encephalitis virus in China. J Gen Virol 88 : 885–894. [Google Scholar]
  18. Teeling EC, Springer MS, Madsen O, Bates P, O’brien SJ, Murphy WJ, 2005. A molecular phylogeny for bats illuminates biogeography and the fossil record. Science 28 : 580–584. [Google Scholar]
  19. Chua KB, Bellini WJ, Rota PA, Harcourt BH, Tamin A, Lam SK, Ksiazek TG, Rollin PE, Zaki SR, Shieh W, Goldsmith CS, Gubler DJ, Roehrig JT, Eaton B, Gould AR, Olson J, Field H, Daniels P, Ling AE, Peters CJ, Anderson LJ, Mahy BW, 2000. Nipah virus: a recently emergent deadly paramyxovirus. Science 288 : 1432–1435. [Google Scholar]
  20. Halpin K, Young PL, Field HE, Mackenzie JS, 2000. Isolation of Hendra virus from pteropid bats: a natural reservoir of Hendra virus. J Gen Virol 81 : 1927–1932. [Google Scholar]
  21. Li W, Shi Z, Yu M, Ren W, Smith C, Epstein JH, Wang H, Crameri G, Hu Z, Zhang H, Zhang J, McEachern J, Field H, Daszak P, Eaton BT, Zhang S, Wang LF, 2005. Bats are natural reservoir of SARS-like coronaviruses. Science 310 : 676–679. [Google Scholar]
  22. Sulkin SE, Allen R, Sims R, Singh KV, 1966. Studies of arthropod-borne virus infections in Chiroptera. IV. The immune response of the big brown bat (Eptesicus f. fuscus) maintained at various environmental temperatures to experimental Japanese B encephalitis virus infection. Am J Trop Med Hyg 15 : 418–427. [Google Scholar]
  23. Miura T, Toyokawa K, Allen R, Sulkin SE, 1970. Studies of arthropod-borne virus infections in chiroptera. VII. Serologic evidence of natural Japanese B encephalitis virus infection in bats. Am J Trop Med Hyg 19 : 88–93. [Google Scholar]
  24. Sulkin SE, Allen R, Sims R, 1963. Studies of arthropod-borne virus infections in chiroptera. I. Susceptibility of insectivorous species to experimental infection with Japanese B and St. Louis encephalitis viruses. Am J Trop Med Hyg 12 : 800–814. [Google Scholar]
  25. Sulkin SE, Sims R, Allen R, 1964. Studies of arthropod-borne virus infections in chiroptera. II. Experiments with Japanese B and St. Louis encephalitis viruses in the gravid bat. Evidence of transplacental transmission. Am J Trop Med Hyg 13 : 475–481. [Google Scholar]
  26. Banerjee K, Ilkal MA, Bhat HR, Sreenivasan MA, 1979. Experimental viraemia with Japanese encephalitis virus in certain domestic and peridomestic vertebrates. Indian J Med Res 70 : 364–368. [Google Scholar]
  27. Banerjee K, Ilkal MA, Deshmukh PK, 1984. Susceptibility of Cynopterus sphinx (frugivorus bat) & Suncus murinus (house shrew) to Japanese encephalitis virus. Indian J Med Res 79 : 8–12. [Google Scholar]
  28. Sulkin SE, Allen R, 1974. Virus infections in bats. Melnick JL, ed. Monographs in Virology. Basel: S. Karger, 1–103.
  29. Simmons NB, 2005. Order Chiroptera. Wilson DE, Reeder DM, eds. Mammal Species of the World. Baltimore, MD: Johns Hopkins University Press, 312–529.
  30. Sulkin SE, Allen R, Sims R, 1966. Studies of arthropod-borne virus infections in Chiroptera. 3. Influence of environmental temperature on experimental infection with Japanese B and St. Louis encephalitis viruses. Am J Trop Med Hyg 15 : 406–417. [Google Scholar]
  31. Holbrook MR, Shope RE, Barrett AD, 2004. Use of recombinant E protein domain III-based enzyme-linked immunosorbent assay for differentiation of tick-borne encephalitis serocomplex flaviviruses from mosquito-borne flaviviruses. J Clin Microbiol 42 : 4101–4110. [Google Scholar]
  32. McLean RG, Ubico SR, Docherty DE, Hansen WR, Sileo L, McNamara TS, 2001. West Nile virus transmission and ecology in birds. White DJ, Morse DL, eds. West Nile Virus: Detection, Surveillance, and Control. Baltimore, MD: Johns Hopkins University Press, 54–57.
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  • Received : 17 Nov 2007
  • Accepted : 29 Jan 2008

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