Volume 77, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


, the most common malarial parasite in sub-Saharan Africa, accounts for a high number of deaths in children less than five years of age. In malaria-endemic countries with stable transmission, semi-immunity is usually acquired after childhood. For adults, severe malaria is rare. Infected adults have either uncomplicated malaria or asymptomatic parasitemia. During a period of one year, we screened 497 afebrile males to investigate the prevalence of asymptomatic parasitemia in villages near Lambaréné, Gabon by use of three different methods. A total of 52% of the individuals had parasites detected by a subtelomeric variable open reading frame polymerase chain reaction (-PCR), 27% of the rapid diagnostic test results were positive, and 12% of the thick blood smears with low parasitemias had . Most positive cases were only detected by the -PCR. Asymptomatic parasitemia in adults living in a malaria-endemic country is frequent.


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  • Received : 22 Oct 2006
  • Accepted : 28 Feb 2007

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