Volume 77, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


We conducted a case-control study to investigate the association between Buruli ulcer (BU) and environmental- and health-related behaviors in southern Benin. Hospital BU cases ( = 324) and sex- and age-matched neighborhood controls ( = 1,173) answered a questionnaire. Regular use of soap for washing, treating injuries with soap or antibiotic powder, and frequent contact with flowing water appeared protective against BU.


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  1. Debacker M, Portaels F, Aguiar J, Steunou C, Zinsou C, Meyers W, Dramaix M, 2006. Risk factors for Buruli ulcer, Benin. Emerg Infect Dis 12 : 1325–1331.
    [Google Scholar]
  2. Raghunathan PL, Whitney EA, Asamoa K, Stienstra Y, Taylor TH Jr, Amofah GK, Ofori-Adjei D, Dobos K, Guarner J, Martin S, Pathak S, Klutse E, Etuaful S, van der Graaf WT, van der Werf TS, King CH, Tappero JW, Ashford DA, 2005. Risk factors for Buruli ulcer disease (Mycobacterium ulcerans Infection): results from a case-control study in Ghana. Clin Infect Dis 40 : 1445–1453.
    [Google Scholar]
  3. Marston BJ, Diallo MO, Horsburgh CR Jr, Diomande I, Saki MZ, Kanga JM, Patrice G, Lipman HB, Ostroff SM, Good RC, 1995. Emergence of Buruli ulcer disease in the Daloa region of Côte d’Ivoire. Am J Trop Med Hyg 52 : 219–224.
    [Google Scholar]
  4. Nackers F, Dramaix M, Johnson RC, Zinsou C, Robert A, Biurrun DE, Bakedano E, Glynn JR, Portaels F, Tonglet R, 2006. BCG vaccine effectiveness against Buruli ulcer: a case-control study in Benin. Am J Trop Med Hyg 75 : 768–774.
    [Google Scholar]
  5. World Health Organization, 2001. Buruli ulcer. Diagnosis of Mycobacterium ulcerans disease. Portaels F, Johnson P, Meyers WM, eds. A Manual for Health Care Providers. Geneva: World Health Organization.
  6. Aiga H, Amano T, Cairncross S, Adomako J, Nanas OK, Coleman S, 2004. Assessing water-related risk factors for Buruli ulcer: a case-control study in Ghana. Am J Trop Med Hyg 71 : 387–392.
    [Google Scholar]
  7. Barker DJ, Ninkibigaya V, 1972. Buruli disease and patients’ activities. East Afr Med J 49 : 260–268.
    [Google Scholar]
  8. Marsollier L, Deniaux E, Brodin P, Marot A, Wondje CM, Saint-Andre JP, Chauty A, Johnson C, Tekaia F, Yeramian E, Legras P, Carbonnelle B, Reysset G, Eyangoh S, Milon G, Cole ST, Aubry J, 2007. Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva. PLoS Med 4 : e64.
    [Google Scholar]

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  • Received : 21 May 2007
  • Accepted : 04 Aug 2007
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