1921
Volume 77, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Seroprevalence of infection in HIV-infected individuals from Shanghai city, Anhui province, and Henan province, China, was examined by enzyme-linked immunosorbent assay using crude antigen and a recombinant surface antigen, C-Igl, of the parasite. In 215 HIV-infected individuals, the positive rates for these antigens were 12.1% and 7.9%, respectively; these rates were significantly higher than the rates of 3.1% and 0.5%, respectively, in 191 patients with gastrointestinal symptoms who were not infected with HIV. There was no significant difference in seropositivity to between men and women. Seropositivity in HIV-infected individuals was higher in patients with a CD4 T cell count of < 200/μL. This is the first report showing a higher seroprevalence of infection in HIV-infected patients in China. Our results also suggest that HIV infection is a risk factor for infection with .

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2007-11-01
2017-11-18
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References

  1. Walsh JA, 1986. Problems in recognition and diagnosis of amebiasis: estimation of the global magnitude of morbidity and mortality. Rev Infect Dis 8 : 228–238.
  2. DuPont HL, Marshall GD, 1995. HIV-associated diarrhoea and wasting. Lancet 346 : 352–356.
  3. Ohnishi K, Kato Y, Imamura A, Fukayama M, Tsunoda T, Sakaue Y, Sakamoto M, Sagara H, 2004. Present characteristics of symptomatic Entamoeba histolytica infection in the big cities of Japan. Epidemiol Infect 132 : 57–60.
  4. Hung CC, Deng HY, Hsiao WH, Hsieh SM, Hsiao CF, Chen MY, Chang SC, Su KE, 2005. Invasive amebiasis as an emerging parasitic disease in patients with human immunodeficiency virus type 1 infection in Taiwan. Arch Intern Med 165 : 409–415.
  5. Hung CC, Chen PJ, Hsieh SM, Wong JM, Fang CT, Chang SC, Chen MY, 1999. Invasive amoebiasis: an emerging parasitic disease in patients infected with HIV in an area endemic for amoebic infection. AIDS 13 : 2421–2428.
  6. World Health Organization, 1997. Entamoeba taxonomy. Bull World Health Organ 75 : 291–294.
  7. Tachibana H, Cheng XJ, Masuda G, Horiki N, Takeuchi T, 2004. Evaluation of recombinant fragments of Entamoeba histolytica Gal/GalNAc lectin intermediate subunit for serodiagnosis of amebiasis. J Clin Microbiol 42 : 1069–1074.
  8. Takeuchi T, Miyahira Y, Kobayashi S, Nozaki T, Motta SR, Matsuda J, 1990. High seropositivity for Entamoeba histolytica infection in Japanese homosexual men: further evidence for the occurrence of pathogenic strains. Trans R Soc Trop Med Hyg 84 : 250–251.
  9. Takeuchi T, Okuzawa E, Nozaki T, Kobayashi S, Mizokami M, Minoshima N, Yamamoto M, Isomura S, 1989. High seropositivity of Japanese homosexual men for amebic infection. J Infect Dis 159 : 808.
  10. Tsai JJ, Sun HY, Ke LY, Tsai KS, Chang SY, Hsieh SM, Hsiao CF, Yen JH, Hung CC, Chang SC, 2006. Higher seroprevalence of Entamoeba histolytica infection is associated with human immunodeficiency virus type 1 infection in Taiwan. Am J Trop Med Hyg 74 : 1016–1019.
  11. Moran P, Ramos F, Ramiro M, Curiel O, Gonzalez E, Valadez A, Gomez A, Garcia G, Melendro EI, Ximenez C, 2005. Infection by human immunodeficiency virus-1 is not a risk factor for amebiasis. Am J Trop Med Hyg 73 : 296–300.
  12. Zheng YL, 1986. An epidemiologic survey on Endoameba histolytica infection. Zhonghua Liu Xing Bing Xue Za Zhi 7 : 274–276.
  13. Zhang TH, 1988. Seroepidemiological study on amoebiasis. Zhonghua Liu Xing Bing Xue Za Zhi 9 : 217–219.
  14. Xu LQ, Yu SH, Xu SH, 1999. Distribution and Pathogenic Impact of Human Parasites in China. Beijing: People’s Medical Publishing House.
  15. Cheng XJ, Tachibana H, Kobayashi S, Kaneda Y, Huang MY, 1993. Pathogenicity of Entamoeba histolytica isolates from Shanghai, China. Parasitol Res 79 : 608–610.
  16. Lowther SA, Dworkin MS, Hanson DL, 2000. Entamoeba histolytica/Entamoeba dispar infections in human immunodeficiency virus-infected patients in the United States. Clin Infect Dis 30 : 955–959.
  17. Cheng XJ, Tsukamoto H, Kaneda Y, Tachibana H, 1998. Identification of the 150-kDa surface antigen of Entamoeba histolytica as a galactose- and N-acetyl-D-galactosamine-inhibitable lectin. Parasitol Res 84 : 632–639.
  18. Cheng XJ, Hughes MA, Huston CD, Loftus B, Gilchrist CA, Lockhart LA, Ghosh S, Miller-Sims V, Mann BJ, Petri WA Jr, Tachibana H, 2001. Intermediate subunit of the Gal/GalNAc lectin of Entamoeba histolytica is a member of a gene family containing multiple CXXC sequence motifs. Infect Immun 69 : 5892–5898.
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  • Received : 13 Mar 2007
  • Accepted : 02 Jul 2007

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