1921
Volume 77, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

We surveyed 236 potentially pathogenic strains, isolated from water sources in the Canary Islands, for the presence of human adenoviruses (HAdV) using a polymerase chain reaction (PCR)-based typing assay. A total of 34 of these strains were found to be positive for adenovirus belonging to four different HAdV serotypes (HAdV-1, 2, 8, and 37). We found that HAdV-2 was the most frequently encountered serotype amongst the strains, and their identification was confirmed by a nested PCR specific for this serotype. We showed that genotype T4 was highly associated with serotype HAdV-2, whereas genotype T3 was most often associated with adenovirus serotypes related to ocular diseases. Based on these data, we suggest that should be considered as a potential reservoir and perhaps even a transmitter of adenoviruses to human and other secondary hosts.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2007.77.753
2007-10-01
2017-11-21
Loading full text...

Full text loading...

/deliver/fulltext/14761645/77/4/0770753.html?itemId=/content/journals/10.4269/ajtmh.2007.77.753&mimeType=html&fmt=ahah

References

  1. Hierholzer JC, 1995. Adenoviruses. Lennette EHLD, Lennette ET, eds. Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections. Seventh edition. Washington, DC: American Public Health Association, 169–188.
  2. Benkö M, Harrach B, Russell WC, 2000. Adenoviridae. Family Adenoviridae. van Regenmortel MHV, Fauquet CM, Bishop DHL, Carstens EB, Estes MK, Lemon SM, Maniloff J, Mayo MA, McGeoch DJ, Pringle CR, Wickner RB, eds. Virus Taxonomy: The Seventh Report of the International Committee on Taxonomy of Viruses. San Diego, CA: Academic Press, pp. 227–238.
  3. Lukashok SA, Horwitz MS, 1998. New perspectives in adenoviruses. Curr Clin Top Infect Dis 18 : 286–305.
  4. Khan NA, 2003. Pathogenesis of Acanthamoeba infection. Microb Pathogen. 34 : 277–285.
  5. Stothard DR, Schroeder-Diedrich JM, Awwad MH, Gast RJ, Ledee DR, Rodriguez-Zaragoza S, Dean CL, Fuerst PA, Byers TJ, 1998. The evolutionary history of the genus Acanthamoeba and the indentification of eight new 18S rRNA gene sequence types. J Eukaryot Microbiol 45 : 45–54.
  6. Horn M, Fritsche TR, Gautom RK, Schleifer K-H, Wagner M, 1999. Novel bacterial endosymbionts of Acanthamoeba spp. related to the Paramecium caudatum symbiont Caedibacter caryophilus. Environ Microbiol 1 : 357–367.
  7. Gast RJ, 2001. Development of an Acanthamoeba-specific reverse dot-blot and the discovery of a new ribotype. J Eukaryot Microbiol 48 : 609–615.
  8. Hewett MK, Robinson BS, Monis PT, Saint CP, 2003. Identification of a new Acanthamoeba 18S rRNA gene sequence type, corresponding to the species Acanthamoeba jacobsi Sawyer, Nerad and Visvesvara, 1992 (Lobosea: Acanthamoebidae). Acta Protozool 42 : 325–329.
  9. Maghsood AH, Sissons J, Rezaian M, Nolder D, Warhurst DC, Khan NA, 2005. Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates. J Med Microbiol 54 : 755–759.
  10. Khan NA, 2006. Acanthamoeba: biology and increasing importance in human health. FEMS Microbiol Rev 30 : 564–595.
  11. Proca-Ciobanu M, Lupascu GH, Petrovici A, Ionescu MD, 1975. Electron microscopic study of a pathogenic Acanthamoeba castellani strain: the presence of bacterial endosymbionts. Int J Parasitol 5 : 49–56.
  12. Drozañski W, Chmielewski T, 1979. Electron microscopic studies of Acanthamoeba castellanii infected with obligate intracellular bacterial parasite. Acta Microbiol Pol 28 : 123–133.
  13. Fritsche TR, Gautom RK, Seyedirashti S, Bergeron DL, Lindquist TD, 1993. Occurence of bacterial endosymbionts in Acanthamoeba spp. isolated from corneal and environmental specimens and contact lenses. J Clin Microbiol 31 : 1122–1126.
  14. Rowbotham TJ, 1980. Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J Clin Pathol 33 : 1179–1183.
  15. Baron D, Danglot C, Vilagines R, 1980. Role of a free-living amoeba from water, Acanthamoaba castellani, in the transport of naked or enveloped animal viruses. C R Seances Acad Sci D 291 : 629–632.
  16. Danes L, Cerva L, 1981. Survival of polioviruses and echoviruses in Acanthamoeba castellanii cultivated in vitro. J Hyg Epidemiol Microbiol Immunol 25 : 169–174.
  17. Mattana A, Serra C, Mariotti E, Delogu G, Fiori PL, Cappuccinelli P, 2006. Acanthamoeba castellanii promotion of in vitro survival and transmission of coxsackie b3 viruses. Eukaryot Cell 5 : 665–671.
  18. Suhre K, 2005. Gene and genome duplication in Acanthamoeba polyphaga Mimivirus. J Virol 79 : 14095–14101.
  19. Rumelt S, Cohen I, Rehany U, 2000. Spontaneous corneal graft ulcerative perforation due to mixed Acanthamoeba and herpes simplex keratitis: A clinicopathologic study. Cornea 19 : 240–242.
  20. Gajdatsy AD, Kosmin A, Barrett GD, 2000. Coexistent adenoviral keratoconjunctivitis and Acanthamoeba keratitis. Clin Experiment Ophthalmol 28 : 434–436.
  21. Lorenzo-Morales J, Ortega-Rivas A, Foronda P, Martínez E, Valladares B, 2005. Isolation and identification of pathogenic Acanthamoeba strains in Tenerife, Canary Islands, Spain from water sources. Parasitol Res 95 : 273–277.
  22. Sambrook J, Fristsch EF, Maniatis T, 1989. Molecular Cloning. A Laboratory Manual. Second edition. New York: Cold Spring Harbor Laboratory Press.
  23. Lu X, Erdman DD, 2006. Molecular typing of human adenoviruses by PCR and sequencing of a partial region of the hexon gene. Arch Virol 151 : 1587–1602.
  24. Puig M, Jofre J, Lucena F, Allard A, Wadell G, Girones R, 1994. Detection of adenoviruses and enteroviruses in polluted waters by nested PCR amplification. Appl Environ Microbiol 60 : 2963–2970.
  25. Lorenzo-Morales J, 2006. Estudios de Amebas de Vida Libre del Genero Acanthamoeba en las Islas Canarias. La Laguna: Universidad de La Laguna.
  26. Greub G, La Scola B, Raoult D, 2004. Amoebae-resisting bacteria isolated from human nasal swabs by amoebal coculture. Emerg Infect Dis. 10 : 470–477.
  27. Greub G, Raoult D, 2004. Microorganisms resistant to free-living amoebae. Clin Microbiol Rev 17 : 413–433.
  28. Amann R, Springer N, Schönhuber W, Ludwig W, Schmid EN, Müller KD, Michel R, 1997. Obligate intracellular bacterial parasites of Acanthamoebae related to Chlamydia spp. Appl Environ Microbiol 63 : 115–121.
  29. La Scola B, Audic S, Robert C, Jungang L, de Lamballerie X, Drancourt M, Birtles R, Claverie JM, Raoult D, 2003. A giant virus in amoebae. Science 299 : 2033.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2007.77.753
Loading
/content/journals/10.4269/ajtmh.2007.77.753
Loading

Data & Media loading...

  • Received : 04 Apr 2007
  • Accepted : 08 May 2007

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error