Volume 77, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


In January 2005, an epidemic of chikungunya fever broke out in the Comoro Islands and lasted until May 2005. In April, cases were also reported in Mayotte and Mauritius. On Réunion Island, the first cases were reported at the end of April. Surveillance of this epidemic required an adaptive system, which at first was based on active and retrospective case detection around the cases reported, then relied on a sentinel network when the incidence increased. Emerging and severe forms of infection were investigated. Death certificates were monitored. By April 2006, the surveillance estimate was 244,000 cases of chikungunya virus infection, including 123 severe cases and 41 of maternoneonatal transmission, with an overall attack rate of 35%. Chikungunya infection was mentioned on 203 death certificates and significant mortality was observed. This epidemic highlighted the need for a mutual strategy of providing information on arboviral diseases and their prevention and control between countries in the southwestern Indian Ocean.


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  1. Robinson MC, 1955. An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952–53. I. Clinical features. Trans R Soc Trop Med Hyg 49 : 28–32. [Google Scholar]
  2. McIntosh BM, Harwin RM, Paterson HE, Westwater ML, 1963. An epidemic of Chikungunya in south-eastern Rhodesia. Cent Afr Med J 43 : 351–359. [Google Scholar]
  3. Roche S, Robin Y, 1967. Human infections by Chikungunya virus in Rufisque (Senegal), October–November, 1966. Bull Soc Med Afr Noire 12 : 490–496. [Google Scholar]
  4. Saluzzo JF, Cornet M, Digoutte JP, 1983. Outbreak of a Chikungunya virus epidemic in western Senegal in 1982. Dakar Med 28 : 497–500. [Google Scholar]
  5. Saluzzo JF, Gonzalez JP, Herve JP, Georges AJ, 1980. Epidemiological study of arboviruses in the Central African Republic: demonstration of Chikungunya virus during 1978 and 1979. Bull Soc Pathol Exot Filiales 73 : 390–399. [Google Scholar]
  6. Thonnon J, Spiegel A, Diallo M, Diallo A, Fontenille D, 1999. Chikungunya virus outbreak in Senegal in 1996 and 1997. Bull Soc Pathol Exot 92 : 79–82. [Google Scholar]
  7. Lam SK, Chua KB, Hooi PS, Rahimah MA, Kumari S, Tharmaratnam M, Chuah SK, Smith DW, Sampson IA, 2001. Chikungunya infection: an emerging disease in Malaysia. Southeast Asian J Trop Med Public Health 32 : 447–451. [Google Scholar]
  8. Chastel C, 1964. Human infection in Cambodia by the chikungunya virus or a closely related agent. 3. Epidemiology. Bull Soc Pathol Exot Filiales 57 : 65–82. [Google Scholar]
  9. Shah KV, Gibbs CJ Jr, Banerjee G, 1964. Virological investigation of the epidemic of haemorrhagic fever in Calcutta: isolation of three strains of chikungunya virus. Indian J Med Res 52 : 676–683. [Google Scholar]
  10. Myers RM, Carey DE, Reuben R, Jesudass ES, De Ranitz C, Jadhav M, 1965. The 1964 epidemic of dengue-like fever in South India: isolation of chikungunya virus from human sera and from mosquitoes. Indian J Med Res 53 : 694–701. [Google Scholar]
  11. Vu-Qui-Dai, Nguyen-Thi Kim-Thoa, Ly-Quoc-Bang, 1967. Study of anti-Chikungunya antibodies in Vietnamese children in Saigon. Bull Soc Pathol Exot Filiales 60 : 353–359. [Google Scholar]
  12. Halstead SB, Scanlon JE, Umpaivit P, Udomsakdi S, 1969. Dengue and chikungunya virus infection in man in Thailand, 1962–1964. IV. Epidemiologic studies in the Bangkok metropolitan area. Am J Trop Med Hyg 18 : 997–1021. [Google Scholar]
  13. Laras K, Sukri NC, Larasati RP, Bangs MJ, Kosim R, Djauzi XX, Wandra T, Master J, Kosasih H, Hartati S, Beckett C, Sedyaningsih ER, Beecham HJ 3rd, Corwin AL, 2005. Tracking the re-emergence of epidemic chikungunya virus in Indonesia. Trans R Soc Trop Med Hyg 99 : 128–141. [Google Scholar]
  14. Pavri KM, 1964. Presence of chikungunya antibodies in human sera collected from Calcutta and Jamshedpur before 1963. Indian J Med Res 52 : 698–702. [Google Scholar]
  15. Thaikruea L, Charearnsook O, Reanphumkarnkit S, Dissomboon P, Phonjan R, Ratchbud S, Kounsang Y, Buranapiyawong D, 1997. Chikungunya in Thailand: a re-emerging disease? Southeast Asian J Trop Med Public Health 28 : 359–364. [Google Scholar]
  16. Pastorino B, Muyembe-Tamfum JJ, Bessaud M, Tock F, Tolou H, Durand JP, Peyrefitte CN, 2004. Epidemic resurgence of Chikungunya virus in democratic Republic of the Congo: identification of a new central African strain. J Med Virol 74 : 277–282. [Google Scholar]
  17. Muyembe-Tamfum JJ, Peyrefitte CN, Yogolelo R, Mathina Basisya E, Koyange D, Pukuta E, Mashako M, Tolou H, Durand JP, 2003. Epidemic of Chikungunya virus in 1999 and 2000 in the Democratic Republic of the Congo. Med Trop 63 : 637–638. [Google Scholar]
  18. Chin J, 2000. Control of Communicable Diseases Manual. Washington, DC: American Public Health Association, 37–39.
  19. Brighton SW, Prozesky OW, de la Harpe AL, 1983. Chikungunya virus infection. A retrospective study of 107 cases. S Afr Med J 63 : 313–315. [Google Scholar]
  20. Mazaud R, Salaun JJ, Montabone H, Goube P, Bazillio R, 1971. Acute neurologic and sensorial disorders in dengue and Chikungunya fever. Bull Soc Path Exot Filiales 64 : 22–30. [Google Scholar]
  21. Pastorino B, Bessaud M, Grandadam M, Murri S, Tolou H, Peyrefitte CN, 2005. Development of a TaqMan RT-PCR assay without RNA extractor step for the detection and quantification of African Chikungunya viruses. J Virol Methods 124 : 65–71. [Google Scholar]
  22. Fourie ED, Morrison JG, 1979. Rheumatoid arthritic syndrome after chikungunya fever. S Afr Med J 56 : 130–132. [Google Scholar]
  23. Josseran L, Paquet C, Zehgnoun A, Caillere N, Le Tertre A, Solet J-L, Ledrans M, 2006. Chikungunya disease outbreak, Reunion Island. Emerg Infect Dis 12 : 1994–1995. [Google Scholar]

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  • Received : 02 Aug 2006
  • Accepted : 16 Apr 2007

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