1921
Volume 77, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

To obtain long-duration protection from mosquitoes using insect repellent N, N-diethyl--toluamide (DEET), this compound was incapsulated during the graft copolymerization of butyl acrylate onto chitosan in an aqueous solution. Morphology of microcapsules was characterized by scanning electron microscopy, scanning probe microscopy, and transmission electron microscopy. This morphology supported successful encapsulation of DEET into polymer capsules. The encapsulation ratio of DEET was greater than 33%, as estimated from thermo-gravimetric results. The aqueous emulsions were applied to cotton textiles by spraying. Treated cloth showed high bactericidal activity against . Mosquito repellency of the bio-cloth was evaluated with . The 90% effective dose of emulsions on textiles was compared with that of DEET in ethanol. A time profile showed that the repellency of an optimized emulsion was 100% after eight hours, and partially preserved even after exposure to air for 48 hours.

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2007-07-01
2017-11-20
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References

  1. Salafsky B, He YX, Li J, Shibuya T, Ramaswamy A, 2000. Study on the efficacy of a new long-acting formulation of N,N-diethyl-m-toluamide (DEET) for the prevention of tick attachment. Am J Trop Med Hyg 62 : 169–172.
  2. Salafsky B, Ramaswamy K, He YX, Anderson GL, Nowicki DK, Shibuya T, 1998. Evaluation of N,N-diethyl-m-toluamide (DEET) as a topical agent for preventing skin penetration by cercariae of Schistosoma mansoni. Am J Trop Med Hyg 58 : 828–834.
  3. Goodyer L, Behrens RH, 1998. The safety and toxicity of insect repellents. Am J Trop Med Hyg 59 : 323–324.
  4. Ma D, Bhattacharjee AK, Gupta RK, Karle JM, 1999. Predicting mosquito repellent potency of N,N-diethyl-m-toluamide (DEET) analogs from molecular electronic properties. Am J Trop Med Hyg 60 : 1–6.
  5. Pennetier C, Corbel V, Hougard JM, 2005. Combination of a non-pyrethroid insecticide and a repellent: a new approach for controlling knockdown-resistant mosquitoes. Am J Trop Med Hyg 72 : 739–744.
  6. Reifenrath WG, Hawkins GS, Kurtz MS, 1990. In vitro evaluation of insect repellent formulations applied to pig skin. Pharmacol Res 7 : 192.
  7. Domb AJ, Marlinsky A, Maniar M, Teomim L, 1995. Insect repellent formulations of N,N-diethyl-m-toluamide (DEET) in a liposphere system: efficacy and skin uptake. J Am Mosq Control Assoc 11 : 29–34.
  8. Gupta RK, Rutledge LC, 1991. Controlled-release repellent formulations on human volunteers under three climatic regimens. J Am Mosq Control Assoc 7 : 490–493.
  9. Rutledge LC, Gupta RK, Mehr ZA, Buescher MD, Reifenrath WG, 1996. Evaluation of controlled-release mosquito repellent formulations. J Am Mosq Control Assoc 12 : 39–44.
  10. Gupta DC, Sumana G, Prakash S, 2000. Polysiloxane based slow release formulations of N,N-diethylphenylacetamide—a broad spectrum insect repellent. J Polym Mater 17 : 215–219.
  11. Iconomopouloua SM, Andreopouloua AK, Sotoa A, Kallitsisa JK, Voyiatzisa GA, 2005. Incorporation of low molecular weight biocodes into polystyrene-divinyl benzene beads with controlled release characteristics. J Control Release 102 : 223–233.
  12. Meilander NJ, Yu X, Ziats NP, Bellamkondaa RV, 2001. Lipid-based microtubular drug delivery vehicles. J Control Release 71 : 141–152.
  13. Badri Viswanathan N, Thomas PA, Pandit JK, Kulkarnia MG, Mashelkarc RA, 1999. Preparation of non-porous micro-spheres with high entrapment efficiency of proteins by a (water-in-oil)-in-oil emulsion technique. J Control Release 58 : 9–20.
  14. Li P, Zhu J, Sunintaboon P, Harris FW, 2002. New route to amphiphilic core-shell polymer nanospheres: graft copolymerization of methyl methacrylate from water-soluble polymer chains containing amino group. Langmuir 18 : 8641–8646.
  15. Fei B, Lu H, Xin JH, 2006. One-step preparation of organosilica@chitosan crosslinked nanospheres. Polymer 47 : 947–950.
  16. Nair SU, 2004. Textile evaluation using biotechnological approach: an overview in Indian textile industry. BTRA Scan 34 : 16–19.
  17. Corporate Test Method 0923, 1979. Midland, MI: Dow Corning.
  18. Neely AN, Maley MP, 2000. Survival of enterococci and staphylococci on hospital fabrics and plastic. J Clin Microbiol 38 : 724–726.
  19. Badolo A, Ilboudo-Sanogo E, Oue’draogo AP, Costantini C, 2004. Evaluation of the sensitivity of Aedes aegypti and Anopheles gambiae complex mosquitoes to two insect repellents: DEET and KBR 3023. Trop Med Int Health 9 : 330–334.
  20. Cockcroft A, Cosgrove JB, Wood RJ, 1998. Comparative repellency of commercial formulations of DEET, permethrin and citronellal against the mosquito Aedes aegypti, using a collagen membrane technique compared with human arm tests. Med Vet Entomol 12 : 289–294.
  21. Prasad MP, Kalyanasundaram M, 1990. Development and evaluation of controlled release formulations of DEPA, an insect repellent. Indian J Med Res (A) 91 : 453–457.
  22. Ye W, Leung MF, Xin J, Kwong TL, Lee DKL, Li P, 2005. Novel core-shell particles with poly (n-butyl acrylate) cores and chi-tosan shells as an antibacterial coating for textiles. Polymer 46 : 10538–10543.
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  • Received : 29 Sep 2006
  • Accepted : 21 Feb 2007

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