1921
Volume 77, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

We describe three instructive cases of neurologic melioidosis that demonstrate the variable nature of clinical manifestations and disease pathology. The appropriate duration and choice of parenteral and oral antimicrobial therapy for neurologic melioidosis are also discussed.

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2007-07-01
2017-09-24
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References

  1. Chaowagul W, White NJ, Dance DA, Wattanagoon Y, Naigowit P, Davis TM, Looareesuwan S, Pitakwatchara N, 1989. Melioidosis: a major cause of community-acquired septicemia in northeastern Thailand. J Infect Dis 159 : 890–899.
  2. Currie BJ, Fisher DA, Howard DM, Burrow JN, Selvanayagam S, Snelling PL, Anstey NM, Mayo MJ, 2000. The epidemiology of melioidosis in Australia and Papua New Guinea. Acta Trop 74 : 121–127.
  3. White NJ, 2003. Melioidosis. Lancet 361 : 1715–1722.
  4. Currie BJ, Fisher DA, Howard DM, Burrow JN, 2000. Neurological melioidosis. Acta Trop 74 : 145–151.
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  7. Wuthiekanun V, Peacock SJ, 2006. Management of melioidosis. Expert Rev Anti Infect Ther 4 : 445–455.
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  9. Klugman KP, Dagan R, 1995. Carbapenem treatment of meningitis. Scand J Infect Dis Suppl 96 : 45–48.
  10. Chierakul W, Anunnatsiri S, Short JM, Maharjan B, Mootsikapun P, Simpson AJ, Limmathurotsakul D, Cheng AC, Stepniewska K, Newton PN, Chaowagul W, White NJ, Peacock SJ, Day NP, Chetchotisakd P, 2005. Two randomized controlled trials of ceftazidime alone versus ceftazidime in combination with trimethoprim–sulfamethoxazole for the treatment of severe melioidosis. Clin Infect Dis 41 : 1105–1113.
  11. Friedrich H, Hansel G, 1977. [An investigation into the levels of a trimethoprim–sulphamethoxazole combination in the ventricular fluid of neurosurgical patients (authors’ transl.)]. Acta Neurochir (Wien) 37 : 271–280.
  12. Andersson H, Alestig K, 1976. The penetration of doxycycline into CSF. Scand J Infect Dis Suppl 17–19.
  13. Limmathurotsakul D, Chaowagul W, Chierakul W, Stepniewska K, Maharjan B, Wuthiekanun V, White NJ, Day NP, Peacock SJ, 2006. Risk factors for recurrent melioidosis in northeast Thailand. Clin Infect Dis 43 : 979–986.
  14. Bakken JS, Bruun JN, Gaustad P, Tasker TC, 1986. Penetration of amoxicillin and potassium clavulanate into the cerebrospinal fluid of patients with inflamed meninges. Antimicrob Agents Chemother 30 : 481–484.
  15. Dance DA, Wuthiekanun V, Chaowagul W, White NJ, 1989. The antimicrobial susceptibility of Pseudomonas pseudomallei. Emergence of resistance in vitro and during treatment. J Antimicrob Chemother 24 : 295–309.
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  • Received : 30 Jan 2007
  • Accepted : 23 Mar 2007

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