Volume 76, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Encephalitis and focal neurologic deficits can occur during the acute phase of schistosomiasis. We report two cases in which cerebral imaging showed cerebral vasculitis located in arterial junctional territories. These neurologic complications may be caused by eosinophil-mediated toxicity. Immediate treatment should consist of corticosteroids rather than specific antischistosomal drugs, which may aggravate the disorders.


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  1. Kane C, Most H, 1948. Schistosomiasis of the central nervous system. Arch Neurol Psychiatr 59 : 141–183. [Google Scholar]
  2. Pittella JE, 1997. Neuroschistosomiasis. Brain Pathol 7 : 649–662. [Google Scholar]
  3. Sarazin M, Caumes E, Cohen A, Amarenco P, 2004. Multiple microembolic borderzone brain infarctions and endomyocardial fibrosis in idiopathic hypereosinophilic syndrome and in Schistosoma mansoni infestation. J Neurol Neurosurg Psychiatry 75 : 305–307. [Google Scholar]
  4. Ferrari TC, 2004. Involvement of central nervous system in the schistosomiasis. Mem Inst Oswaldo Cruz 99 : 59–62. [Google Scholar]
  5. Vachon F, Jebrak G, Boulu P, Coulaud JP, 1984. Manifestations précoces sévères d’une bilharziose à S. mansoni. A propos d’un cas avec échec du traitement précoce par le praziquentel. Med Mal Infect 14 : 102–106. [Google Scholar]
  6. Kirchhoff LV, Nash TE, 1984. A case of schistosomiasis japonica: resolution of CAT-scan detected cerebral abnormalities without specific therapy. Am J Trop Med Hyg 33 : 1155–1158. [Google Scholar]
  7. Granier H, Potard M, Diraison P, Nicolas X, Laborde JP, Talarmin F, 2003. Acute encephalitis concurrent with primary infection by Schistosoma mansoni. Med Trop (Mars) 63 : 60–63. [Google Scholar]
  8. Pittella JE, 1991. The relation between involvement of the central nervous system in schistosomiasis mansoni and the clinical forms of the parasitosis. A review. J Trop Med Hyg 94 : 15–21. [Google Scholar]
  9. Saladi R, Persaud A, Rudikoff D, Cohen S, 2004. Idiopathic splinter hemorhages. J Am Acad Dermatol 50 : 289–292. [Google Scholar]
  10. Gay T, Pankey GA, Beckman EN, Washington P, Bell KA, 1982. Fatal CNS trichinosis. JAMA 247 : 1024–1025. [Google Scholar]
  11. Fourestie V, Douceron H, Brugieres P, Ancelle T, Lejonc JL, Gherardi RK, 1993. Neurotrichinosis. A cerebrovascular disease associated with myocardial injury and hypereosinophilia. Brain 116 : 603–616. [Google Scholar]
  12. Brito-Babapulle F, 2003. The eosinophilias, including the idiopathic hypereosinophilic syndrome. Br J Haematol 121 : 203–223. [Google Scholar]
  13. Leiferman KM, Gleich GJ, 2004. Hypereosinophilic syndrome: case presentation and update. J Allergy Clin Immunol 113 : 50–58. [Google Scholar]
  14. Corradi D, Vaglio A, Maestri R, Legname V, Leonardi G, Bartoloni G, Buzio C, 2004. Eosinophilic myocarditis in a patient with idiopathic hypereosinophilic syndrome: insights into mechanisms of myocardial cell death. Hum Pathol 35 : 1160–1163. [Google Scholar]
  15. Kartha CC, 1995. Endomyocardial fibrosis, a case for the tropical doctor. Cardiovasc Res 30 : 636–643. [Google Scholar]
  16. Kwon SU, Kim JC, Kim JS, 2001. Sequential magnetic resonance imaging findings in hypereosinophilia-induced encephalopathy. J Neurol 248 : 279–284. [Google Scholar]
  17. Grandiere-Perez L, Ansart S, Paris L, Faussart A, Jaureguiberry S, Grivois JP, Klement E, Bricaire F, Danis M, Caumes E, 2006. Efficacy of praziquantel during the incubation and invasive phase of Schistosoma haematobium schistosomiasis in 18 travelers. Am J Trop Med Hyg 74 : 814–818. [Google Scholar]

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  • Received : 07 Aug 2006
  • Accepted : 28 Dec 2006

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