1921
Volume 76, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

We report a fatal case of anicteric leptospirosis with pancreatitis (acute hyperglycemia and insulin requirement, elevated lipase and amylase levels), pulmonary infiltrates, and refractory shock. In disease-endemic areas, leptospirosis with pancreatitis should be considered in patients with fever and abdominal pain, and serum pancreatic enzymes, blood glucose, and serum electrolytes should be closely monitored.

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/content/journals/10.4269/ajtmh.2007.76.886
2007-05-01
2017-11-18
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References

  1. Vincent J, O’Brien M, Person DA, Cook BA, 1999. Leptospirosis and pancreatitis. Pediatr Infect Dis J 18 : 400–403.
  2. Kaya E, Dervisoglu A, Eroglu C, Polat C, Sunbul M, Ozkan K, 2005. Acute pancreatitis caused by leptospirosis: report of two cases. World J Gastroenterol 11 : 447–449.
  3. O’Brien MM, Vincent JM, Person DA, Cook BA, 1998. Leptospirosis and pancreatitis: a report of ten cases. Pediatr Infect Dis J 17 : 436–438.
  4. Edwards CN, Evarard CO, 1991. Hyperamylasemia and pancreatitis in leptospirosis. Am J Gastrol 86 : 1665–1668.
  5. American Diabetes Association, 2005. Diagnosis and classification of diabetes mellitus. Diabetes Care 28 (Suppl 1): 37–42.
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  7. Wilson PG, Manji M, Neoptolemos JP, 1998. Acute pancreatitis as a model of sepsis. J Antimicrob Chemother 41 : 51–63.
  8. Pitchumoni CS, Patel NM, Shah P, 2005. Factors influencing mortality in acute pancreatitis: can we alter them? J Clin Gastroenterol 39 : 798–814.
  9. Niederau C, Hippennstiel J, 2006. Conservative management of acute pancreatitis: complications and outcome in a community-based hospital. Pancreas 32 : 67–79.
  10. Nathens AB, Curtis JR, Beale RJ, Cook DJ, Moreno RP, Romand JA, Skerrett SJ, Stapleton RD, Ware LB, Waldmann CS, 2004. Management of the critical ill patient with severe acute pancreatitis. Crit Care Med 32 : 2524–2536.
  11. Judkowski VA, Allicotti GM, Sarvetnick N, Pinilla C, 2004. Peptides from common viral and bacterial pathogens can efficiently activate diabetogenic T-cells. Diabetes 53 : 2301–2309.
  12. Levett PN, 2001. Leptospirosis. Clin Microbiol Rev 14 : 296–326.
  13. Bharti AR, Nally JE, Ricaldi JN, Matthias MA, Diaz MM, Lovett MA, Levett PN, Gilman RH, Willig MR, Gotuzzo E, Vinetz JM, 2003. Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis 3 : 757–771.
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  • Received : 09 Jun 2006
  • Accepted : 05 Feb 2007

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