Volume 76, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Malaria is a major public health problem in French Guiana. This study was conducted in children <1–5 years of age in Camopi, an Amerindian village in eastern French Guiana. Medical, environmental, and behavioral predictive factors of malaria were studied using the Kaplan-Meier method and Cox modeling. Variables included were clearing vegetation around the home (hazard ratio [HR] = 0.62, 95% confidence interval [CI] = 0.43–0.88 for 50–75% cleared and HR = 0.5, 95% CI = 0.31–0.81 for > 75% cleared) relative to homes surrounded by vegetation; distance of a home from a river (HR = 0.56, 95% CI = 0.37–0.85 for distances between 20 and 40 meters, HR = 0.72, 95% CI = 0.47–1.09 for distances between 40 and 80 meters, HR = 0.52, 95% CI = 0.28–0.94 for distances between 80 and 120 meters, and HR = 0.5, 95% CI = 0.30–0.86 for distances > 120 meters) relative to distances < 20 meters; the number of occupants in the home (HR = 1.54, 95% CI = 0.98–2.44 for 7 occupants, HR = 1.9, 95% CI = 1.29–2.81 for 8–11 occupants, and HR = 2.03, 95% CI = 1.27–3.23 for > 11 occupants); clothing (HR = 0.64, 95% CI = 0.46–0.90 for children wearing western-style clothes relative to those wearing the traditional kalimbe), and ethnicity (Wayampi children had a lower hazard of malaria relative to Emerillon children: HR = 0.55, 95% CI = 0.40–0.80). The environment near the home was strongly associated with malaria. This suggests that simple pragmatic protection measures would be useful in Camopi.


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  1. Carme B, Venturin C, 1999. Malaria in the Americas. Med Trop (Mars) 59 : 298–302. [Google Scholar]
  2. Carme B, 2005. Substancial increase of malaria in inland areas of eastern French Guiana. Trop Med Int Health 10 : 154–159. [Google Scholar]
  3. Harris AF, Matias-Arnèz A, Hill N, 2006. Biting time of Anopheles darlingi in the Bolivian Amazon and implications for control of malaria. Trans R Soc Trop Med Hyg 100 : 45–47. [Google Scholar]
  4. Tadei WP, Thatcher BD, Santos JM, Scarpassa VM, Brandao Rodrigues I, Silva Rafael M, 1998. Ecologic observations on anopheline vectors of malaria in the Brazilian Amazon. Am J Trop Med Hyg 59 : 325–335. [Google Scholar]
  5. Carme B, Lecat J, Lefebvre P, 2005. Malaria in an outbreak zone in Oyapock (French Guiana): incidence of malaria attacks in the Amerindian population of Camopi. Med Trop (Mars) 65 : 149–154. [Google Scholar]
  6. Brooker S, Clarke S, Njagi JK, Polack S, Mugo B, Estambale B, Muchiri E, Magnussen P, Cox J, 2004. Spatial clustering of malaria and associated risk factors during an epidemic in a highland area of western Kenya. Trop Med Int Health 9 : 757–766. [Google Scholar]
  7. Van Der Hoek W, Konradsen F, Amerasinghe PH, Perera D, Piyaratne MK, Amerasinghe FP, 2003. Toward a risk map of malaria for Sri Lanka: the importance of house location relative to vector bredding sites. Int J Epidemiol 32 : 280–285. [Google Scholar]
  8. Staedke SG, Nottingham EW, Cox J, Kamya MR, Rosenthal PJ, Dorsey G, 2003. Short report: proximity to mosquito breeding sites as a risk factor for clinical malaria episodes in an urban cohort of Ugandan children. Am J Trop Med Hyg 69 : 244–246. [Google Scholar]
  9. Kleinschmidt I, Sharp BL, Clarke GP, Curtis B, Fraser C, 2001. Use of generalized linear models in the spatial analysis of small-area malaria incidence rate in Kwazulu Natal, South Africa. Am J Epidemiol 153 : 1213–1221. [Google Scholar]
  10. Hakre S, Masuoka P, Vanzie E, Roberts DR, 2004. Spatial correlations of mapped malaria rates with environmental factors in Belize, Central America. Int J Health Geogr 22 : 3–6. [Google Scholar]
  11. Barrera R, Grillet ME, Rangel Y, Berti J, Aché A, 1999. Temporal and spatial patterns of malaria reinfection in northeastern Venezuela. Am J Trop Med Hyg 61 : 784–790. [Google Scholar]
  12. Nacher M, McGready R, Stepniewska K, Cho T, Looareesuwan S, White NJ, Nosten F, 2003. Haematinic treatment of anaemia increases the risk of Plasmodium vivax malaria in pregnancy. Trans R Soc Trop Med Hyg 97 : 273–276. [Google Scholar]
  13. Sazawal S, Black RE, Ramsan M, Chwaya HM, Stoltzfuz R, Dutta A, Dhingra U, Kabole I, Deb S, Othman M, Kabole FM, 2006. Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in high malaria transmission setting: Community-based, randomised, placebo-controlled trial. Lancet 367 : 133–143. [Google Scholar]
  14. Nacher M, 2005. Charming the mosquito: do malaria symptoms increase the attractiveness of the host vector? Med Hypotheses 64 : 788–791. [Google Scholar]
  15. Klinkenberg E, van Der Hoek W, Amerasinghe FP, 2004. A malaria risk analysis in an irrigated area in Sri Lanka. Acta Trop 89 : 215–225. [Google Scholar]
  16. Van der Hoek W, Konradsen F, Amerasinghe PH, Perera D, Piyaratne MK, Amerasinghe FP, 2003. Toward a risk map of malaria for Sri Lanka: the importance of house location relative to vector breeding sites. Int J Epidemiol 32 : 280–285. [Google Scholar]
  17. Raccurt CP, 1997. Malaria, Anopheles, the anti-malaria campaign in French Guiana: between dogmatism and judgment. Med Trop (Mars) 57 : 401–406. [Google Scholar]
  18. Garcia A, Dieng AB, Rouget F, Migot-Nabias F, Le Hesran JY, Gaye O, 2004. Role of environment and behaviour resemblances of Plasmodium falciparum infection in a population of Senegalese children. Microbes Infect 6 : 68–75. [Google Scholar]
  19. Smith DL, Duschoff J, Snow RW, Hay SI, 2005. The entomological inoculation rate and Plasmodium falciparum infection in African children. Nature 438 : 492–495. [Google Scholar]

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  • Received : 22 Jun 2006
  • Accepted : 31 Oct 2006

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