Volume 76, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Field and laboratory studies were carried out in October and November 2005 to provide a comparative evaluation of the performance of three rapid malaria detection tests, two of which were recently introduced (the CareStart™ Malaria test and the SD Malaria Antigen Bioline™ test) and the well-known OptiMAL-IT™ test. Compared with microscopy, the sensitivity of the three tests to detect malaria was 97% for the CareStart™ Malaria test, 89.4% for the SD Malaria Antigen Bioline™ test, and 92.6% for the OptiMAL-IT™ test. The three tests were less sensitive in detecting non- infections, and the sensitivity decreased at levels of parasitemia ≤ 500 parasites/μL for and ≤ 5,000 parasites/μL for other spp. On the basis of World Health Organization recommendations, only the CareStart™ Malaria test and the OptiMAL-IT™ test had sensitivities greater than 95% for samples with parasitemias ≥ 100 parasites/μL.


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  • Received : 24 May 2006
  • Accepted : 24 Oct 2006

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