1921
Volume 76, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

We estimated the swine cysticercosis risk gradient surrounding tapeworm carriers in seven rural communities in Peru. At baseline, the prevalences of taeniasis by microscopy and swine cysticercosis by serology were 1.2% (11 of 898) and 30.8% (280 of 908), respectively. The four-month cumulative seroincidence was 9.8% (30 of 307). The unadjusted swine seroprevalence and seroincidence rates increased exponentially by 12.0% (95% confidence [CI] = 9.7–14.3%) and 32.8% (95% CI = 25.0–41.0%), respectively when distance to carriers decreased by half. Swine seroprevalence was 18.4% at > 500 meters from a carrier, 36.5% between 51 and 500 meters, and 68.9% within 50 meters ( < 0.001). Swine seroincidence also displayed a strong gradient near tapeworm carriers (3.8%, 12.2%, and 44.0%; < 0.001). Within 50 meters, swine seroprevalence appeared unaffected if the owners harbored tapeworms, although pigs owned by a tapeworm carrier had a four times higher seroincidence compared with other pigs ( = 0.005). In rural areas, swine cysticercosis occurs in high-risk hotspots around carriers where control interventions could be delivered.

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2007-02-01
2017-11-17
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References

  1. Garcia HH, Gonzalez AE, Evans CA, Gilman RH; Cysticercosis Working Group in Peru., 2003. Taenia solium cysticercosis. Lancet 362 : 547–556.
  2. Bern C, Garcia HH, Evans C, Gonzalez AE, Verastegui M, Tsang VC, Gilman RH, 1999. Magnitude of the disease burden from neurocysticercosis in a developing country. Clin Infect Dis 29 : 1203–1209.
  3. Diaz Camacho SP, Candil Ruiz A, Suate Peraza V, Zazueta Ramos ML, Felix Medina M, Lozano R, Willms K, 1991. Epidemiologic study and control of Taenia solium infections with praziquantel in a rural village of Mexico. Am J Trop Med Hyg 45 : 522–531.
  4. Sarti E, Schantz PM, Plancarte A, Wilson M, Gutierrez IO, Lopez AS, Roberts J, Flisser A, 1992. Prevalence and risk factors for Taenia solium taeniasis and cysticercosis in humans and pigs in a village in Morelos, Mexico. Am J Trop Med Hyg 46 : 677–685.
  5. Garcia HH, Gilman RH, Tovar MA, Flores E, Jo R, Tsang VC, Diaz F, Torres P, Miranda E, 1995. Factors associated with Taenia solium cysticercosis: analysis of nine hundred forty-six Peruvian neurologic patients. Cysticercosis Working Group in Peru (CWG). Am J Trop Med Hyg 52 : 145–148.
  6. Garcia-Noval J, Allan JC, Fletes C, Moreno E, DeMata F, Torres-Alvarez R, Soto de Alfaro H, Yurrita P, Higueros-Morales H, Mencos F, Craig PS, 1996. Epidemiology of Taenia solium taeniasis and cysticercosis in two rural Guatemalan communities. Am J Trop Med Hyg 55 : 282–289.
  7. Cao W, van der Ploeg CP, Xu J, Gao C, Ge L, Habbema JD, 1997. Risk factors for human cysticercosis morbidity: a population-based case-control study. Epidemiol Infect 119 : 231–235.
  8. Sanchez AL, Gomez O, Allebeck P, Cosenza H, Ljungstrom L, 1997. Epidemiological study of Taenia solium infections in a rural village in Honduras. Ann Trop Med Parasitol 91 : 163–171.
  9. Diaz Camacho S, Candil Ruiz A, Uribe Beltran M, Willms K, 1990. Serology as an indicator of Taenia solium tapeworm infections in a rural community in Mexico. Trans R Soc Trop Med Hyg 84 : 563–566.
  10. Garcia HH, Gilman RH, Gonzalez AE, Verastegui M, Rodriguez S, Gavidia C, Tsang VC, Falcon N, Lescano AG, Moulton LH, Bernal T, Tovar M; Cysticercosis Working Group in Peru, 2003. Hyperendemic human and porcine Taenia solium infection in Peru. Am J Trop Med Hyg 68 : 268–275.
  11. Sarti-Gutierrez EJ, Schantz PM, Lara-Aguilera R, Gomez Dandoy H, Flisser A, 1988. Taenia solium taeniasis and cysticercosis in a Mexican village. Trop Med Parasitol 39 : 194–198.
  12. Gemmell MA, Johnstone PD, 1976. Factors regulating tapeworm populations: dispersion of eggs of Taenia hydatigena on pasture. Ann Trop Med Parasitol 70 : 431–434.
  13. Lawson JR, Gemmell MA, 1983. Hydatidosis and cysticercosis: the dynamics of transmission. Adv Parasitol 22 : 261–308.
  14. Sansom BF, Gleed PT, 1981. The ingestion of sow’s faeces by suckling piglets. Br J Nutr 46 : 451–456.
  15. Gleed PT, Sansom BF, 1982. Ingestion of iron in sow’s faeces by piglets reared in farrowing crates with slotted floors. Br J Nutr 47 : 113–117.
  16. Cooper J, Gordon IJ, Pike AW, 2000. Strategies for the avoidance of faeces by grazing sheep. Appl Anim Behav Sci 69 : 15–33.
  17. Hutchings MR, Athanasiadou S, Kyriazakis I, Gordon IJ, 2003. Can animals use foraging behaviour to combat parasites? Proc Nutr Soc 62 : 361–370.
  18. Instituto Nacional de Estadistica e Informatica, 1993. III Censo de Poblacion y Vivienda—Informe Final (Spanish). Lima, Peru: Instituto Nacional de Estadistica e Informatica.
  19. Pearson RD, Hewlett EL, 1985. Niclosamide therapy for tapeworm infections. Ann Intern Med 102 : 550–551.
  20. Ritchie LS, 1948. An ether sedimentation technique for routine stool examination. Bull US Army Med Department 8 : 326.
  21. Gonzalez AE, Falcon N, Gavidia C, Garcia HH, Tsang VC, Bernal T, Romero M, Gilman RH, 1998. Time-response curve of oxfendazole in the treatment of swine cysticercosis. Am J Trop Med Hyg 59 : 832–836.
  22. Engel HN, Claire LE, 1986. Anatomy. Leman AD, Straw BE, Mengeling WL, eds. Diseases of Swine. Ames, IA: Iowa State University Press, 3–25.
  23. Tsang VC, Brand JA, Boyer AE, 1989. An enzyme-linked immunoelectrotransfer blot assay and glycoprotein antigens for diagnosing human cysticercosis (Taenia solium). J Infect Dis 159 : 50–59.
  24. Tsang VC, Pilcher JA, Zhou W, Boyer AE, Kamango-Sollo EI, Rhoades ML, Murrell KD, Schantz PM, Gilman RH, 1991. Efficacy of the immunoblot assay for cysticercosis in pigs and modulated expression of distinct IgM/IgG activities to Taenia solium antigens in experimental infections. Vet Immunol Immunopathol 29 : 69–78.
  25. Garcia HH, Gonzalez AE, Gavidia C, Falcon N, Bernal T, Verastegui M, Rodriguez S, Tsang VC, Gilman RH; Cysticercosis Working Group in Peru., 2003. Seroincidence of porcine T. solium infection in the Peruvian highlands. Prev Vet Med 57 : 227–236.
  26. Microsoft Encarta Online Encyclopedia, 2004. Latitude and Longitude. Redmond, WA: Microsoft Corporation. Available from http://encarta.msn.com
  27. Nelder JA, Wedderburn RWM, 1972. Generalized linear models. J R Stat Soc Ser A 135 : 370–384.
  28. Gonzalez AE, Verastegui M, Noh JC, Gavidia C, Falcon N, Bernal T, Garcia HH, Tsang VC, Gilman RH, Wilkins PP, 1999. Persistence of passively transferred antibodies in porcine Taenia solium cysticercosis. Cysticercosis Working Group in Peru. Vet Parasitol 86 : 113–118.
  29. Gemmell MA, Johnstone PD, Boswell CC, 1978. Factors regulating tapeworm populations: dispersion patterns of Taenia hydatigena eggs on pasture. Res Vet Sci 24 : 334–338.
  30. Gonzalez AE, Lopez-Urbina T, Tsang BY, Gavidia CM, Garcia HH, Silva ME, Ramos DD, Manzanedo R, Sanchez-Hidalgo L, Gilman RH, Tsang VC, 2005. Secondary transmission in porcine cysticercosis: description and their potential implications for control sustainability. Am J Trop Med Hyg 73 : 501–503.
  31. Allan JC, Wilkins PP, Tsang VC, Craig PS, 2003. Immunodiagnostic tools for taeniasis. Acta Trop 87 : 87–93.
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  • Received : 19 Sep 2006
  • Accepted : 26 Oct 2006

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