Volume 75, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


We present evidence that a parasite with characteristics of is being transmitted among Duffy blood group–negative inhabitants of Kenya. Thirty-two of 4,901 and (0.65%) collected in Nyanza Province were ELISA positive for the circumsporozoite protein VK 247. All positives were found late in the rainy season, when predominated, and disproportionately many were found at a single village. A specific sequence of the SSU rRNA gene was amplified from three of six ELISA-positive mosquitoes. Erythrocytes from 31 children, including 9 microscopically diagnosed as infected with , were negative by flow cytometry for the Fy3 or Fy6 epitopes, which indicate Duffy blood group expression. A DNA fragment specific for the C terminus of the gene for merozoite surface protein 1 (MSP-1) was amplified from the blood of four of these children and subsequently sequenced from two.


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  • Received : 14 Apr 2006
  • Accepted : 23 May 2006

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