1921
Volume 75, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Outbreaks of bovine vaccinia disease caused by circulation of (VACV) strains have been a common occurrence in Brazil in the recent years, being an important emergent zoonosis. During a single outbreak that took place in 2001, two genetically different VACV strains were isolated and named Guarani P1 virus (GP1V) and Guarani P2 virus (GP2V). Molecular diagnosis was done through restriction fragment length polymorphism (RFLP) of gene (A26L) and by sequence analysis of a group of five VACV genes including the , , , , and genes. These findings confirmed the co-circulation of two different strains during the same outbreak, raising important questions about the origin, emergence, and circulation of VACV strains in Brazil.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2006.75.486
2006-09-01
2017-09-22
Loading full text...

Full text loading...

/deliver/fulltext/14761645/75/3/0750486.html?itemId=/content/journals/10.4269/ajtmh.2006.75.486&mimeType=html&fmt=ahah

References

  1. Damaso CRA, Esposito JJ, Condit R, Moussatché N, 2000. An emergent poxvirus from humans and cattle in Rio de Janeiro state: Cantagalo virus may derive from Brazilian smallpox vaccine. Virology 277 : 439–449.
  2. Leite JA, Drumond BP, Trindade GS, Lobato ZIP, da Fonseca FG, dos Santos JR, Madureira MC, Guedes MIMC, Ferreira JMS, Bonjardim CA, Ferreira PC, Kroon EG, 2005. Passatempo virus: a novel Vaccinia virus isolated during a zoonotic outbreak in Brazil. Emerg Infect Dis 11 : 1935–1938.
  3. Lobato ZIP, Trindade GS, Frois MCM, Ribeiro EBT, Dias GRC, Teixeira BM, Lima FA, Almeida GMF, Kroon EG, 2005. Outbreak of exantemal disease caused by Vaccinia virus in human and cattle in Zona da Mata Region, Minas Gerais. Arq Bras Med Vet Zootech 57 : 423–429.
  4. Nagasse-Sugahara TK, Kisielius JJ, Ueda-Ito M, & 8 other authors 2004. Human vaccinia-like virus outbreaks in Sao Paulo and Goias States, Brazil: Virus detection, isolation and identification. Rev Inst Med Trop Sao Paulo 46 : 315–322.
  5. Schatzmayr HG, Lemos ER, Mazur C, Schubach A, Majerowicz S, Rozental T, Schubach TM, Bustamente MC, Barth OM, 2000. Detection of poxvirus in cattle associated with human cases in the State of Rio de Janeiro: Preliminary report. Mem Inst Oswaldo Cruz 95 : 625–627.
  6. Trindade GS, Fonseca FG, Marques JT, Nogueira ML, Mendes LC, Borges AS, Pituco EM, Bonjardim CA, Ferreira PC, Kroon EG, 2003. Araçatuba virus: A vaccinia-like virus associated with cattle and human infection. Emerg Infect Dis 9 : 155–160.
  7. Malkin AJ, McPherson A, Gershon PD, 2003. Structure of intra-cellular mature vaccinia virus vizsualized by in situ atomic force microscopy. J Virol 77 : 6332–6340.
  8. Meyer H, Roop SL, Esposito JJ, 1997. Gene for A-type inclusion body protein is useful for a polymerase chain reaction assay to differentiate orthopoxvirus. J Virol Meth 64 : 217–221.
  9. Neubauer H, Pfeffer M, Meyer H, 1997. Specific detection of mousepox virus by polymerase chain reaction. Lab Anim Sci 31 : 201–205.
  10. Marques JT, Trindade GS, da Fonseca FG, dos Santos JR, Bonjardim CA, Ferreira PCP, Kroon EG, 2001. Characterization of ATI, TK and IFN-alpha/betaR genes in the genome of the BeAn 58058 virus, a naturally attenuated wild Orthopoxvirus. Virus Genes 23 : 291–301.
  11. Trindade GS, da Fonseca FG, Marques JT, Diniz S, Leite JA, De Bodt S, Van der Peer Y, Bonjardim CA, Ferreira PCP, Kroon EG, 2004. Belo Horizonte virus: A vaccinia-like virus lacking the A-type inclusion body gene isolated from infected mice. J Gen Virol 85 : 2015–2021.
  12. da Fonseca FG, Trindade GS, Silva RLA, Bonjardim CA, Ferreira PCP, Kroon EG, 2002. Characterization of a vaccinia-like virus isolated in a Brazilian forest. J Gen Virol 83 : 223–228.
  13. Fonseca FG, Lanna MCS, Campos MAS, Kitajima EW, Peres JN, Golgher RR, Ferreira PCP, Kroon EG, 1998. Morphological and molecular characterization of the poxvirus BeAn 58058. Arch Virol 143 : 1171–1186.
  14. Roop SL, Jin QI, Knight JC, Massung RF, Esposito JJ, 1995. PCR strategy for identification and differentiation of smallpox and other Orthopoxviruses. J Clin Microbiol 33 : 2069–2076.
  15. Goebel SJ, Johson GP, Perkus ME, Davis SW, Winslow JP, Paoletti E, 1990. The complete DNA sequence of vaccinia virus. Virology 179 : 247–266.
  16. Johnson GP, Goebel SJ, Paoletti E, 1993. An update on the Vaccinia virus genome. Virology 381 : 381–401.
  17. Sanger F, Nicklen S, Coulson AR, 1977. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74 : 5463–5467.
  18. Huang X, Madan A, 1999. CAP3: A DNA sequence assembly program. Genome Res 9 : 868–877.
  19. Pearson W. LALIGN-find multiple matching subsegments in two sequences. http://www.ch.embnet.org/software/LALIGN_form.html. Accessed January 2006.
  20. Thompson JD, Higgins DG, Gibson TJ, 1994. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22 : 4673–4680.
  21. Tamura K, Nei M, 1993. Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Mol Biol Evol 10 : 512–526.
  22. Kumar S, Tamura K, Nei M, 2004. MEGA3: Integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinform 5 : 150–163.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2006.75.486
Loading
/content/journals/10.4269/ajtmh.2006.75.486
Loading

Data & Media loading...

  • Received : 15 Feb 2006
  • Accepted : 10 May 2006

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error