1921
Volume 75, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

We assessed morbidity indicators for both and infections and evaluated the appropriateness of the World Health Organization (WHO) guidelines for ultrasound in schistosomiasis in the context of large-scale control interventions. Abdominal and urinary tract ultrasonography was performed on 2,247 and 2,822 school children, respectively, from 29 randomly selected schools in Mali before the implementation of mass anthelminthic drug administration. Using two-level logistic regression models, we examined associations of potential factors with the risk of having a positive ultrasound global score (morbidity indicative of infection), abnormal image pattern scores, dilatation of the portal vein, and/or enlarged liver (morbidity indicative of infection). The WHO protocol was found useful for detection of pathology but overestimated the risk of portal vein dilatation and left liver lobe enlargement associated with infection. We conclude that ultrasonography should be included in large-scale control interventions, where logistics allow, but cautiously.

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2006-12-01
2017-07-24
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  • Received : 28 Feb 2006
  • Accepted : 22 Jun 2006

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