Volume 74, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Although is increasingly recognized as an important cause of morbidity in pregnancy in low malaria–transmission areas of Asia, little is know about the epidemiologic and clinical profiles of in pregnant women in Latin America. We describe the clinical features and pregnancy outcomes in a series of 12 cases of malaria in pregnant women complicated in some by miscarriage or preterm deliveries and in others with significant degrees of anemia and thrombocytopenia in a population where is endemic in northeastern Venezuela.


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  1. Nosten F, Rogerson SJ, Beeson JG, McGready R, Mutabingwa TK, Brabin B, 2004. Malaria in pregnancy and the endemicity spectrum. Trends Parasitol 20 : 425–432.
  2. Steketee RW, Nahlen BL, Parise ME, Menendez C, 2001. The burden of malaria in pregnancy in malaria-endemic areas. Am J Trop Med Hyg 62 (Suppl): 28–35.
  3. Brabin BJ, Romagosa C, Abdelgalil S, Menendez C, Verhoeff FH, McGready R, Fletcher KA, Owens S, D’Alessandro U, Nosten F, Fischer PR, Ordi J,2004. The sick placenta—the role of malaria. Placenta 25 : 359–378.
  4. Beeson JG, Rogerson SJ, Elliott SR, Duffy MF, 2005. Targets of protective antibodies to malaria during pregnancy. J Infect Dis 192 : 1647–1650.
  5. Whitty CJ, Edmonds S, Mutabingwa TK, 2005. Malaria in pregnancy. BJOG 112 : 1189–1195.
  6. Luxemburger C, McGready R, Kham Am, Morison L, Cho T, Chongsuphajaisiddhi T, White NJ, Nosten F, 2001. Effects of malaria during pregnancy on infant mortality in an area of low malaria transmission. Am J Epidemiol 154 : 459–465.
  7. Newman RD, Parise ME, Slutsker L, Nahlen B, Steketee W, 2003. Safety, efficacy and determinants of effectiveness of antimalarial drugs during pregnancy: Implications for prevention programmes in Plasmodium falciparum-endemic sub-Saharan Africa. Trop Med Int Health 8 : 488–506.
  8. Tako EA, Zhou A, Lohoue J, Leke R, Taylor DW, Leke RF, 2005. Risk factors for placental malaria and its effect on pregnancy outcome in Yaonde, Cameroon. Am J Trop Med Hyg 72 : 236–242.
  9. Kalanda BF, Verhoeff FH, Chimsuku L, Harper G, Brabin BJ, 2005. Adverse birth outcomes in a malarious area. Epidemiol Infect 28 : 1–8.
  10. Nosten F, McGready R, Simpson JA, Thwai KL, Balkan S, Cho T, Hkirijaroen L, Looareesuwan S, White NJ, 1999. Effects of Plasmodium vivax malaria in pregnancy. Lancet 354 : 546–549.
  11. Singh N, Shukla MM, Sharma VP, 1999. Epidemiology of malaria in pregnancy in central India. Bull World Health Organ 77 : 567–572.
  12. Kochar DK, Saxena V, Singh N, Kochar SK, Kumar SV, Das A, 2005. Plasmodium vivax malaria. Emerg Infect Dis 11 : 132–134.
  13. Sina B, 2002. Focus on Plasmodium vivax. Trends Parasitol 18 : 287–289.
  14. Rodriguez-Morales AJ, Delgado L, Martinez N, Franco-Paredes C, 2006. Impact of imported malaria on the burden of disease in northeastern Venezuela. J Travel Med 13 : 15–20.
  15. Luxemburger C, Ricci F, Raimond D, Bathet S, White NJ, 1997. The epidemiology of severe malaria in an area of low transmission in Thailand. Trans R Soc Trop Med Hyg 91 : 256–262.
  16. Rodriguez-Morales AJ, Sanchez E, Vargas M, Piccolo C, Colina R, Arria M, Franco-Paredes C, 2005. Occurrence of thrombocytopenia in Plasmodium vivax malaria. Clin Infect Dis 41 : 130–131.
  17. Rodriguez-Morales AJ, Sanchez E, Vargas M, Piccolo C, Colina R, Arria M, 2004. Epidemiology of Plasmodium vivax malaria in hospitalized children, Sucre, Venezuela. Int J Infect Dis 8 (Suppl): S144.
  18. Sanchez E, Vargas M, Piccolo C, Colina R, Arria M, Blanco JJ, Rodriguez-Morales A, 2004. Malaria por Plasmodium vivax en adultos hospitalizados en Carúpano, Sucre, 2000–2002. Salus Militiae 29 : 55–61.
  19. Mohapatra MK, Padhiary KN, Mishra DP, Sethy G, 2002. Atypical manifestations of Plasmodium vivax malaria. Indian J Malariol 39 : 18–25.
  20. Collins WE, Jeffery GM, Roberts JM, 2003. A retrospective examination of anemia during infection of humans with Plasmodium vivax. Am J Trop Med Hyg 68 : 410–412.
  21. Song HH, So O, Kim SH, Moon SH, Kim JB, Yoon JW, Koo JR, Hong KS, Lee MG, Kim DJ, Shin DH, Kang SH, Choi MG, Lee KH,2003. Clinical features of Plasmodium vivax malaria. Korean J Intern Med. 18 : 220–224.
  22. Rodriguez-Morales AL, 2004. Malaria y embarazo en Venezuela: aspectos clinico-epidemiológicos de una realidad poco estudiada. Academia 2 : 15–20.
  23. Martinez-Espinosa FE, Daniel-Ribeiro CT, Alecrim WD, 2004. Malaria during pregnancy in a reference centre from the Brazilian Amazon: unexpected increase in the frequency of Plasmodium falciparum infections. Mem Inst Oswaldo Cruz 99 : 19–21.
  24. Duffy PE, 2003. Plasmodium falciparum adhesion in the placenta. Curr Opin Microbiol 6 : 371–376.
  25. Nacher M, McGready R, Stepniewska K, Cho T, Looaresuwan S, White J, Nosten F, 2003. Haematinic treatment of anaemia increases the risk of Plasmodium vivax malaria in pregnancy. Trans R Soc Trop Med Hyg 97 : 273–276.

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  • Received : 29 Sep 2005
  • Accepted : 29 Nov 2005

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