1921
Volume 74, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

We performed a retrospective study of 164 human immunodeficiency virus (HIV)–infected patients with disseminated histoplasmosis to identify the risk factors for death. Death occurred in 32% of the cases. Univariate analysis identified the following risk factors: diarrhea (odds ratio [OR] = 3.9, = 0.001), neurologic manifestations (OR = 5.8, ; = 0.001), hemoglobin level < 8.0g/dL (OR = 2.7, = 0.004), urea level 2 times the normal upper limit (OR = 5.0, < 0.001), creatinine level > 1.5 mg/dL (OR = 2.9, = 0.005), aspartate aminotransferase (AST) level > 2.5 times the normal upper limit (OR = 3.1, = 0.01), respiratory insufficiency (OR = 9.7, < 0.001), sepsis (OR = 20.2, < 0.001), and acute renal failure (OR = 2.5, = 0.011). A hemoglobin level < 8.0 g/dL (OR = 3.8, = 0.008), an AST level ≥ 2.5 times the normal limit (OR = 1.0, = 0.007), acute renal failure (OR = 2.96, = 0.015), and respiratory insufficiency (OR = 12.2, = 0.01) were independent risk factors for death.

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2006-04-01
2017-11-17
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  • Received : 21 Sep 2005
  • Accepted : 15 Oct 2005

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