1921
Volume 74, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

From March 2000 to February 2002, a population-based study of type b (Hib) meningitis was conducted among children less than five years of age in Hanoi, Vietnam. Children with suspected bacterial meningitis were referred to hospitals and each patient underwent standardized clinical examination and microbiologic testing. In Hanoi, 580 children were evaluated for bacterial meningitis and 23 (4%) had confirmed or probable Hib meningitis. The incidence of all Hib meningitis was 12/100,000 child-years less than five years of age and 26/100,000 child-years less than two years of age. Nationally, an estimated 1,005 children less than five years of age are hospitalized for Hib meningitis and 5,107 are hospitalized for Hib pneumonia. Among children with Hib meningitis, at least 100 will develop severe neurologic sequelae and 40 will die. These data suggest there is a substantial burden of Hib disease in Vietnam. National leaders will be provided with these data to facilitate development of national vaccination policies for children in Vietnam.

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2006-03-01
2017-11-20
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References

  1. Jamison DT, Mosley WH, Measham AR, Bobadilla JL, 1993. Disease control priorities in developing countries. Stansfield SK, Shepard DS, eds. Acute Respiratory Infection. Second edition. New York: Oxford University Press, 67–90.
  2. Anon., 1998. Global programme for vaccines and immunization (GPV). The WHO position paper on Haemophilus influenzae type b conjugate vaccines. Wkly Epidemiol Rec 73 : 64–68.
  3. de la Hoz F, Higuera AB, Di Fabio JL, Luna M, Naranjo AG, de lL V, Pastor D, Hall AJ, 2004. Effectiveness of Haemophilus influenzae type b vaccination against bacterial pneumonia in Colombia. Vaccine 23 : 36–42.
  4. Martin M, Casellas JM, Madhi SA, Urquhart TJ, Delport SD, Ferrero F, Chamany S, Dayan GH, Rose CE, Levine OS, Klugman KP, Feikin DR, 2004. Impact of Haemophilus influenzae type b conjugate vaccine in South Africa and Argentina. Pediatr Infect Dis J 23 : 842–847.
  5. McVernon J, Howard AJ, Slack MP, Ramsay ME, 2004. Long-term impact of vaccination on Haemophilus influenzae type b (Hib) carriage in the United Kingdom. Epidemiol Infect 132 : 765–767.
  6. Hviid A, Melbye M, 2004. Impact of routine vaccination with a conjugate Haemophilus influenzae type b vaccine. Vaccine 22 : 378–382.
  7. Peltola H, Aavitsland P, Hansen KG, Jonsdottir KE, Nokleby H, Romanus V, 1999. Perspective: a five-country analysis of the impact of four different Haemophilus influenzae type b conjugates and vaccination strategies in Scandinavia. J Infect Dis 179 : 223–229.
  8. Tran TT, Le QT, Tran TN, Nguyen NT, Pedersen FK, Schlumberger M, 1998. The etiology of bacterial pneumonia and meningitis in Vietnam. Pediatr Infect Dis J 17 : S192–S194.
  9. Larsson M, Kronvall G, Chuc NT, Karlsson I, Lager F, Hanh HD, Tomson G, Falkenberg T, 2000. Antibiotic medication and bacterial resistance to antibiotics: a survey of children in a Vietnamese community. Trop Med Int Health 5 : 711–721.
  10. Central Census Steering Committee, 2000. 1999 Population and Housing Census: Sample Results. Hanoi, Vietnam.
  11. Sarff LD, Platt LH, McCracken GH Jr, 1976. Cerebrospinal fluid evaluation in neonates: comparison of high-risk infants with and without meningitis. J Pediatr 88 : 473–477.
  12. Oski FA, 1999. Laboratory values. Oski’s Pediatrics: Principles and Practice. Third edition. New York: Lippincott Williams and Wilkins, 2216–2224.
  13. Levine O, Schuchat A, Schwartz B, Wenger JD, Elliott J, 1996. Generic Protocol for Population-Based Surveillance of Haemophilus influenzae type b. Geneva: World Health Organization. WHO/VRD/GEN/95.05.
  14. Daly J, Seskin KC, Pezzlo M, 1992. Processing and interpretation of cerebrospinal fluid. Isenberg HD, ed. Clinical Microbiology Procedures Handbook. First edition. Washington, DC: American Society for Microbiology Press, 67–72.
  15. Murray PR, Baron EJ, Pfaller MA, Tenover PC, Yolken RH, 1995. Manual of Clinical Microbiology. Sixth edition. Washington, DC: American Society for Microbiology Press, 301–561.
  16. Kim JS, Jang YT, Kim JD, Park TH, Park JM, Kilgore PE, Kennedy WA, Park E, Nyambat B, Kim DR, Hwang PH, Kim SJ, Eun SH, Lee HS, Cho JH, Kim YS, Chang SJ, Huang HF, Clemens JD, Ward JI, 2004. Incidence of Haemophilus influenzae type b and other invasive diseases in South Korean children. Vaccine 22 : 3952–3962.
  17. National Committee for Clinical Laboratory Standards, 2000. NCCLS Quality Manual. Wayne, PA: NCCLS.
  18. Salo P, Ortqvist A, Leinonen M, 1995. Diagnosis of bacteremic pneumococcal pneumonia by amplification of pneumolysin gene fragment in serum. J Infect Dis 171 : 479–482.
  19. Newcombe RG, 1998. Interval estimation for the difference between independent proportions: comparison of eleven methods. Stat Med 17 : 873–890.
  20. World Health Organization, 2004. Estimating the Local Burden of Haemophilus influenzae Type b (Hib) Disease Preventable by Vaccination. A Rapid Assessment Tool. Geneva: World Health Organization. Wor(WHO/V&B/01.27), 1–67.
  21. Mulholland K, Hilton S, Adegbola R, Usen S, Oparaugo A, Omosigho C, Weber M, Palmer A, Schneider G, Jobe K, Lahai G, Jaffar S, Secka O, Lin K, Ethevenaux C, Greenwood B, 1997. Randomised trial of Haemophilus influenzae type-b tetanus protein conjugate vaccine [corrected] for prevention of pneumonia and meningitis in Gambian infants. Lancet 349 : 1191–1197.
  22. Levine OS, Lagos R, Munoz A, Villaroel J, Alvarez AM, Abrego P, Levine MM, 1999. Defining the burden of pneumonia in children preventable by vaccination against Haemophilus influenzae type b. Pediatr Infect Dis J 18 : 1060–1064.
  23. Kanegaye JT, Soliemanzadeh P, Bradley JS, 2001. Lumbar puncture in pediatric bacterial meningitis: defining the time interval for recovery of cerebrospinal fluid pathogens after parenteral antibiotic pretreatment. Pediatrics 108 : 1169–1174.
  24. Stuertz K, Merx I, Eiffert H, Schmutzhard E, Mader M, Nau R, 1998. Enzyme immunoassay detecting teichoic and lipoteichoic acids versus cerebrospinal fluid culture and latex agglutination for diagnosis of Streptococcus pneumoniae meningitis. J Clin Microbiol 36 : 2346–2348.
  25. Cao XT, Ngo TN, Kneen R, Bethell D, Le TD, Nguyen TT, Pham TT, Truong DL, Solomon T, Wills B, Parry CM, 2004. Evaluation of an algorithm for integrated management of childhood illness in an area of Vietnam with dengue transmission. Trop Med Int Health 9 : 573–581.
  26. Ward JI, Margolis HS, Lum MK, Fraser DW, Bender TR, Anderson P, 1981. Haemophilus influenzae disease in Alaskan Eskimos: characteristics of a population with an unusual incidence of invasive disease. Lancet 1 : 1281–1285.
  27. Hanna JN, Wild BE, 1991. Bacterial meningitis in children under five years of age in Western Australia. Med J Aust 155 : 160–164.
  28. Rerks-Ngam S, Treleaven S, Chunsuttiwat S, Muangchana C, Jolley D, Brooks A, Dejiselert S, Varintarwat S, Guiver M, Kunasol P, Maynard JE, Biggs B, Steinhoff M, 2004. Prospective population-based incidence of Haemophilus influenzae type b meningitis in Thailand. Vaccine 22 : 975–983.
  29. Yang Y, Shen X, Jiang Z, Liu X, Leng Z, Lu D, Rao J, Liu J, Chang L, 1998. Study on Haemophilus influenzae type b diseases in China: the past, present and future. Pediatr Infect Dis J 17 : S159–S165.
  30. Vutuc C, Kunze M, 1993. Incidence of Haemophilus influenzae meningitis in Austria. Wien Klin Wochenschr 105 : 59–60.
  31. Simarro E, Ruiz J, Gomez J, Ortega MG, Vicente C, Martinez L, Perez J, 2000. Haemophilus influenzae infections in children less than 5 years of age in the community of Murcia during the 1992–1999 period. Enferm Infecc Microbiol Clin 18 : 325–328.
  32. Syrogiannopoulos GA, Mitselos CJ, Beratis NG, 1995. Childhood bacterial meningitis in southwestern Greece: a population-based study. Clin Infect Dis 21 : 1471–1473.
  33. Gessner BD, Sutanto A, Linehan M, Djelantik IG, Fletcher T, Gerudug IK, Ingerani , Mercer D, Moniaga V, Moulton LH, Moulton LH, Mulholland K, Nelson C, Soemohardjo S, Steinhoff M, Widjaya A, Stoeckel P, Maynard J, Arjoso S, 2005. Incidences of vaccine-preventable Haemophilus influenzae type b pneumonia and meningitis in Indonesian children: hamlet-randomised vaccine-probe trial. Lancet 365 : 43–52.
  34. Prasad K, Singhal T, Jain N, Gupta PK, 2004. Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis. Cochrane Database Syst Rev CD001832.
  35. Marcon MJ, Hamoudi AC, Cannon HJ, 1984. Comparative laboratory evaluation of three antigen detection methods for diagnosis of Haemophilus influenzae type b disease. J Clin Microbiol 19 : 333–337.
  36. Scheifele DW, Daum RS, Syriopoulou VP, Siber GR, Smith AL, 1979. Comparison of two antigen detection techniques in a primate model of Haemophilus influenzae type b infection. Infect Immun 26 : 827–831.
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  • Received : 28 Sep 2005
  • Accepted : 20 Oct 2005

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