Volume 74, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


A single 40 mg/kg dose of praziquantel (PZQ) continues to be the standard treatment for schistosomiasis caused by and in all clinical settings. Experimental development of drug resistance and the recent isolation of strains with a natural tolerance to high doses of PZQ have raised concerns over the adequacy of such a dose. We describe two Spanish travelers with genitourinary schistosomiasis caused by in whom repeated standard treatment failed to clear the infection.


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  • Received : 05 Aug 2005
  • Accepted : 26 Aug 2005
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