1921
Volume 74, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

is a major cause of diarrhea among children in developing countries. Since free-ranging chickens are a major source of infections, we hypothesized that corralling of these chickens would result in decreased rates of infections and -related diarrhea. We tested this hypothesis in Peruvian families in a periruban shantytown with free-ranging chickens and randomized by household using a (corralling) intervention versus control study design. Samples from participants and chickens were cultured for at the start of surveillance, and samples from children less than six years of age with diarrhea episodes and two sentinel chickens were cultured for monthly. Overall, 4,257 human stool specimens and 3,950 avian stool specimens were cultured over a 17-month period. Rates of -related diarrhea in children were significantly higher in the corral group, which demonstrated twice the incidence of diarrhea compared with controls overall, and seven times the rate of diarrhea versus controls in the subset with more than 20 household chickens. Rates of asymptomatic infection with were similar. Although corralling may be useful if corrals are distant from living quarters, it is not advisable as a control measure for in communities such as this.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.2006.74.1054
2006-06-01
2017-09-25
Loading full text...

Full text loading...

/deliver/fulltext/14761645/74/6/0741054.html?itemId=/content/journals/10.4269/ajtmh.2006.74.1054&mimeType=html&fmt=ahah

References

  1. Oberhelman RA, Taylor D, 1999. Campylobacter infections in developing countries. Blaser MJ, Nachamkin I, eds. Campylobacter. Washington, DC: American Society for Microbiology Press, 139–154.
  2. Oberhelman RA, Gilman RH, Taylor DN, Black RE, Sheen P, Cabrera L, Madico G, Lescano AG, 1999. A placebo-controlled trial of Lactobacillus GG to prevent diarrhea in Peruvian children. J Pediatr 134 : 15–20.
  3. Black RE, Lopez de Romana G, Brown KH, Bravo N, Bazalar OG, Kanashiro HC, 1989. Incidence and etiology of infantile diarrhea and major routes of transmission in Huascar, Peru. Am J Epidemio 129 : 785–799.
  4. Guerrant RL, Hughes J, Lima N, Crane J, 1990. Diarrhea in developed and developing countries: magnitude, special settings, and etiologies. Rev Infect Dis 12 : S41–S50.
  5. Skirrow MB, Blaser MJ, 1995. Campylobacter jejuni. Blaser M, Smith PD, Ravdin JI, Greenberg HB, Guerrant RL, eds. Infections of the Gastrointestinal Tract. First edition. New York: Raven Press, 825–848.
  6. Grados O, Bravo N, Black RE, Butzler JP, 1988. Paediatric Campylobacter diarrhea from household exposure to live chickens in Lima, Peru. Bull World Health Organ 66 : 369–374.
  7. Marquis GS, Ventura G, Gilman RH, Porras E, Miranda E, Carbajal L, Pentafiel M, 1990. Fecal contamination of shantytown toddlers in households with non-corralled poultry, Lima, Peru. Am J Public Health 80 : 146–149.
  8. Harvey SA, Winch PJ, Leontsini E, Torres Gayoso C, López Romero S, Gilman RM, Oberhelman RA, 2003. Domestic poultry raising practices in a Peruvian shantytown: implications for control of Campylobacter jejuni-associated diarrhea. Acta Trop 86 : 41–54.
  9. Oberhelman RA, Gilman RH, Sheen P, Cordova J, Taylor DN, Zimic M, Meza R, Perez J, LeBron C, Cabrera L, Rodgers FG, Woodward DL, Price LJ, 2003. Campylobacter transmission in a Peruvian periurban shantytown: a longitudinal study of Campylobacter isolates from chickens and human in household clusters using molecular and serological strain typing techniques. J Infect Dis 187 : 260–269.
  10. Zeger SL, Liang K-Y, Albert PS, 1988. Models for longitudinal data: a generalized estimating equation approach. Biometrics 44 : 1049–1060.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.2006.74.1054
Loading
/content/journals/10.4269/ajtmh.2006.74.1054
Loading

Data & Media loading...

  • Received : 11 Jun 2004
  • Accepted : 20 Feb 2006

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error