1921
Volume 74, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

We assessed the seroprevalence of infection using indirect hemagglutination antibody (IHA) assay among 667 HIV-infected persons (group A), 1,311 asymptomatic HIV-uninfected persons seeking anonymous HIV testing (group B), 616 HIV-uninfected controls with gastrointestinal symptoms (diarrhea and/or liver abscess) seeking medical care (group C), and 2,500 healthy controls undergoing health check-up (group D). An IHA titer ≥ 128 was detected in 7.1% of group A, 2.5% of group B, 1.8% of group C, and 0.1% of group D ( < 0.0001). The highest seroprevalence (11.2%) was noted among HIV-infected persons who were men having sex with men (MSM) 30–39 years of age. Compared with persons with gastrointestinal symptoms, the adjusted odds ratio for having high IHA titers among HIV-infected persons was 3.206 (95% confidence interval, 1.433, 7.176; = 0.005). These findings show that HIV-infected persons, especially MSM 30–39 years of age, are at significantly higher risk of infection.

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  • Received : 15 Nov 2005
  • Accepted : 19 Feb 2006

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