Volume 73, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Tetrodotoxication was observed in six patients who ate gastropods from the South China Sea near Pratas Island. The pathogenic gastropod was , which had not been previously mentioned in human tetrodotoxication. An extremely high level of tetrodotoxin was found in the causative gastropods, and a variety of clinical signs were observed in the survivors. The postmortem autopsy of two patients showed severe distension and hypersecretion of the alimentary tract, suggestive of a cholinergic crisis as the cause of their early death. A recognition of education regarding the risk of tetrodotoxication by in the study area is important to prevent further tragedy. A retrospective review of the tetrodotoxication in this region may aid in understanding the changes and route of tetrodotoxication in marine products, and provide valuable information for preventive measures.


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  • Received : 06 Mar 2005
  • Accepted : 25 Jun 2005

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